Investigation on sulfanilamide and its interaction with some metals and lincomycin by infrared spectroscopy

In this work, the new cobalt and cadmium complexes of sulfanilamide were prepared and investigated by infrared spectrocopy. Their infrared spectra were compared with x-ray powder diffraction patterns of the complexes. The vibrations due to the anilino and sulfonamido groups are shifted with respect to the free sulfanilamide molecule in line with their coordination to the metal atoms. In addition, the low energy calculations were also carried out by using geometry optimization. The proposed structure for the complexes derived from the infrared spectra are consistent with the x-ray powder diffraction measurements and theoretical calculations. Among the studies, drug compounds, sulfanilamide-lincomycine interaction was obtained in methanol solution. The predicted structure of the product was given as a result of infrared studies.