Advances in prenatal screening: the ethical dimension

被引：91
作者：
de Jong, Antina [1 ,2 ,5 ]
Dondorp, Wybo J. [1 ,2 ,3 ]
Frints, Suzanna G. M. [2 ,4 ]
de Die-Smulders, Christine E. M. [2 ,4 ]
de Wert, Guido M. W. R. [1 ,2 ,3 ,5 ]
机构：
[1] Maastricht Univ, Dept Hlth Eth & Soc, NL-6200 MD Maastricht, Netherlands
[2] Maastricht Univ, Sch Oncol & Dev Biol, GROW, NL-6200 MD Maastricht, Netherlands
[3] Maastricht Univ, CAPHRI, Sch Publ Hlth & Primary Care, NL-6200 MD Maastricht, Netherlands
[4] Maastricht Univ, Med Ctr AzM, Dept Clin Genet, NL-6202 MZ Maastricht, Netherlands
[5] Ctr Soc & Genom, NL-6500 GL Nijmegen, Netherlands
来源：
NATURE REVIEWS GENETICS | 2011年 / 12卷 / 09期
关键词：
GENOMIC HYBRIDIZATION ACGH; MATERNAL PLASMA; FETAL DNA; DIAGNOSIS; ANEUPLOIDY; GUIDELINES; FETUSES; LESS; TIME; PCR;
D O I：
10.1038/nrg3036
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Prenatal screening strategies are undergoing rapid changes owing to the introduction of new testing techniques. The overall tendency is towards broadening the scope of prenatal testing through increasingly sensitive ultrasound scans and genome-wide molecular tests. In addition, non-invasive prenatal diagnosis is likely to be introduced in the near future. These developments raise important ethical questions concerning meaningful reproductive choice, the autonomy rights of future children, equity of access and the proportionality of testing.
引用
收藏
页码：657 / 663
页数：7
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