Inhibition of the NF-κB Pathway in Human Intestinal Epithelial Cells by Commensal Streptococcus salivarius

被引：70

作者：

Kaci, Ghalia ^{[2
]}

Lakhdari, Omar ^{[1
]}

Dore, Joel ^{[1
]}

Ehrlich, S. Dusko ^{[2
]}

Renault, Pierre ^{[2
]}

Blottiere, Herve M. ^{[1
]}

Delorme, Christine ^{[2
]}

机构：

[1] INRA, Funct Intestinal Ecosyst Grp, Micalis UMR1319, F-78352 Jouy En Josas, France

[2] INRA, Commensal & Food Bacteria Grp, Micalis UMR1319, F-78352 Jouy En Josas, France

来源：

APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2011年 / 77卷 / 13期

关键词：

INFLAMMATORY RESPONSES; IMMUNE-RESPONSES; BACTERIA; LACTOBACILLUS; PROBIOTICS; STRAINS;

D O I：

10.1128/AEM.03021-10

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Streptococcus salivarius exhibited an anti-inflammatory effect on intestinal epithelial cells (IECs) and monocytes. Strains were screened using a reporter clone, HT-29/kB-luc-E, induced by tumor necrosis factor alpha (TNF-alpha). Supernatant from each strain downregulated NF-kappa B activation. The two most efficient strains produced an active metabolite (<3 kDa) which was able to downregulate the secretion of the proinflammatory chemokine interleukin-8 (IL-8).

引用

页码：4681 / 4684

页数：4

共 50 条

[1] Inhibition of DRA Expression by NF-κB Pathway in Human Intestinal Epithelial Cells
Kumar, Anoop
Alakkam, Anas
Gill, Ravinder K.
Gujral, Tarunmeet
Soni, Vinay
Anbazhagan, Arivarasu Natarajan
Malakooti, Jaleh
Alrefai, Waddah A.
Dudeja, Pradeep K.
GASTROENTEROLOGY, 2013, 144 (05) : S664 - S665
[2] Commensal Streptococcus salivarius Modulates PPARγ Transcriptional Activity in Human Intestinal Epithelial Cells
Couvigny, Benoit
de Wouters, Tomas
Kaci, Ghalia
Jacouton, Elsa
Delorme, Christine
Dore, Joel
Renault, Pierre
Blottiere, Herve M.
Guedon, Eric
Lapaque, Nicolas
PLOS ONE, 2015, 10 (05):
[3] Piceatannol Alleviates Deoxynivalenol-Induced Damage in Intestinal Epithelial Cells via Inhibition of the NF-κB Pathway
Zhu, Min
Lu, En-Qing
Fang, Yong-Xia
Liu, Guo-Wei
Cheng, Yu-Jie
Huang, Ke
Xu, E.
Zhang, Yi-Yu
Wang, Xiao-Jing
MOLECULES, 2024, 29 (04):
[4] Surface proteins involved in the adhesion of Streptococcus salivarius to human intestinal epithelial cells
Fanny Chaffanel
Florence Charron-Bourgoin
Claire Soligot
Mounira Kebouchi
Stéphane Bertin
Sophie Payot
Yves Le Roux
Nathalie Leblond-Bourget
Applied Microbiology and Biotechnology, 2018, 102 : 2851 - 2865
[5] Surface proteins involved in the adhesion of Streptococcus salivarius to human intestinal epithelial cells
Chaffanel, Fanny
Charron-Bourgoin, Florence
Soligot, Claire
Kebouchi, Mounira
Bertin, Stephane
Payot, Sophie
Le Roux, Yves
Leblond-Bourget, Nathalie
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2018, 102 (06) : 2851 - 2865
[6] Activation of NF-κB by NOD2 in human intestinal epithelial cells
Vogel, Tiphanie P.
Lodolce, James P.
Logsdon, Mark
Bartulis, Sarah
Burn, Melisa
Schneider, Jeff
Kolodziej, Lauren
Messer, Jeannette S.
Chang, Jonathan
Boone, David L.
GASTROENTEROLOGY, 2008, 134 (04) : A357 - A357
[7] Genomics of Streptococcus salivarius, a major human commensal
Delorme, Christine
Abraham, Anne-Laure
Renault, Pierre
Guedon, Eric
INFECTION GENETICS AND EVOLUTION, 2015, 33 : 381 - 392
[8] Identification of NF-κB Modulation Capabilities within Human Intestinal Commensal Bacteria
Lakhdari, Omar
Tap, Julien
Beguet-Crespel, Fabienne
Le Roux, Karine
de Wouters, Tomas
Cultrone, Antonietta
Nepelska, Malgorzata
Lefevre, Fabrice
Dore, Joel
Blottiere, Herve M.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, 2011, : 1 - 9
[9] Inhibition of the pro-inflammatory NF-κB pathway by a grape seed and grape marc meal extract in intestinal epithelial cells
Gessner, D. K.
Ringseis, R.
Siebers, M.
Keller, J.
Kloster, J.
Wen, G.
Eder, K.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION, 2012, 96 (06) : 1074 - 1083
[10] Adenosine is a negative regulator of NF-κB and MAPK signaling in human intestinal epithelial cells
Jijon, HB
Walker, J
Hoentjen, F
Diaz, H
Ewaschuk, J
Jobin, C
Madsen, KL
CELLULAR IMMUNOLOGY, 2005, 237 (02) : 86 - 95

← 1 2 3 4 5 →