Synthesis of vinca alkaloids and related compounds, LXXXVII. Reversed enantioselectivity in different approaches

被引：0

作者：

Szabo, L ^{[1
]}

Nagy, T ^{[1
]}

Kalaus, G ^{[1
]}

Szantay, C ^{[1
]}

机构：

[1] Tech Univ Budapest, Inst Organ Chem, H-1521 Budapest, Hungary

来源：

ACH-MODELS IN CHEMISTRY | 1998年 / 135卷 / 04期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Using the same chiral auxiliaries during the enantioselective synthesis of vincamine the absolute configuration depends on the selected approach. Starting from Wenkert enamine the natural (+)-vincamine, while using the reaction sequence through vincadifformine type intermediate, the (-)-enantiomer is formed.

引用

页码：641 / 651

页数：11

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