Microwave-Assisted Preparation of β-Cyclodextrin-Based Stationary Phase for Open Tubular Capillary Electrochromatography

被引：6

作者：

Hongjun, E. ^{[1
]}

Su, Ping ^{[1
]}

Farooq, Muhammad Umar ^{[1
]}

Yang, Yi ^{[1
]}

机构：

[1] Beijing Univ Chem Technol, Coll Sci, Beijing 100029, Peoples R China

来源：

ANALYTICAL LETTERS | 2010年 / 43卷 / 15期

基金：

中国国家自然科学基金;

关键词：

beta-cyclodextrin derivative; Fluorescein isothiocyanate; Microwave-assisted; Open tubular capillary electrochromatography; BONDED-SILICA PARTICLES; CHIRAL SEPARATION; ENANTIOMERIC SEPARATIONS; ELECTROPHORESIS; CHROMATOGRAPHY; DRUGS; ENANTIOSEPARATION; HPLC; SFC;

D O I：

10.1080/00032711003725532

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Fluorescein isothiocyanate was used as a label to show that a 3-aminopropylmethyldimethoxysilane (KH 550)-modified capillary column was prepared by microwave irradiation. A bromoacetate-substituted beta-cyclodextrin (Br-beta-CD) was successfully bound to the KH 550-modified column as a chiral stationary phase for open tubular capillary electrochromatography. Compared with conventional synthesis, the microwave-assisted process significantly decreased the preparation time of the stationary phase from 16h to 40min. Baseline chiral separation of 1-phenyl-1,2-ethanediol was achieved using the Br-beta-CD modified column.

引用

页码：2372 / 2380

页数：9

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