Ribosome assembly in eukaryotes

被引：498
作者：
Fromont-Racine, M
Senger, B
Saveanu, C
Fasiolo, F
机构：
[1] Inst Pasteur, CNRS, URA 2171, F-75724 Paris 15, France
[2] CNRS, Inst Biol Mol & Cellulaire, UPR 9002, F-67084 Strasbourg, France
来源：
GENE | 2003年 / 313卷
关键词：
rRNA maturation; nucleolus; regulation; transport; late steps; assembly; PUTATIVE RNA HELICASE; SMALL NUCLEOLAR RIBONUCLEOPROTEIN; NUCLEAR-PORE COMPLEX; TEMPERATURE-SENSITIVE MUTATIONS; TRANSLATION INITIATION-FACTOR; STEADY-STATE LEVELS; SACCHAROMYCES-CEREVISIAE; YEAST HOMOLOG; BINDING PROTEIN; U3; SNORNP;
D O I：
10.1016/S0378-1119(03)00629-2
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Ribosome synthesis is a highly complex and coordinated process that occurs not only in the nucleolus but also in the nucleoplasm and the cytoplasm of eukaryotic cells. Based on the protein composition of several ribosomal subunit precursors recently characterized in yeast, a total of more than 170 factors are predicted to participate in ribosome biogenesis and the list is still growing. So far the majority of ribosomal factors have been implicated in RNA maturation (nucleotide modification and processing). Recent advances gave insight into the process of ribosome export and assembly. Proteomic approaches have provided the first indications for a ribosome assembly pathway in eukaryotes and confirmed the dynamic character of the whole process. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：17 / 42
页数：26
相关论文
共 220 条
[1]   Saccharomyces cerevisiae nucleolar protein Nop7p is necessary for biogenesis of 60S ribosomal subunits [J].
Adams, CC ;
Jakovljevic, J ;
Roman, J ;
Harnpicharnchai, P ;
Woolford, JL .
RNA, 2002, 8 (02) :150-165
[2]   A hierarchy of RNA subdomains in assembly of the central domain of the 30 S ribosomal subunit [J].
Agalarov, SC ;
Williamson, JR .
RNA, 2000, 6 (03) :402-408
[3]   Structure of the S15,S18-rRNA complex: Assembly of the 30S ribosome central domain [J].
Agalarov, SC ;
Prasad, GS ;
Funke, PM ;
Stout, CD ;
Williamson, JR .
SCIENCE, 2000, 288 (5463) :107-112
[4]  
Agris PF, 1996, PROG NUCLEIC ACID RE, V53, P79, DOI 10.1016/S0079-6603(08)60143-9
[5]   STRUCTURAL REQUIREMENTS OF 5S RIBOSOMAL-RNA FOR NUCLEAR TRANSPORT, 7S RIBONUCLEOPROTEIN PARTICLE ASSEMBLY, AND 60S RIBOSOMAL-SUBUNIT ASSEMBLY IN XENOPUS-OOCYTES [J].
ALLISON, LA ;
NORTH, MT ;
MURDOCH, KJ ;
ROMANIUK, PJ ;
DESCHAMPS, S ;
LEMAIRE, M .
MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (11) :6819-6831
[6]  
Andersen JS, 2002, CURR BIOL, V12, P1, DOI 10.1016/S0960-9822(01)00650-9
[7]   Yeast Rio1p is the founding member of a novel subfamily of protein serine kinases involved in the control of cell cycle progression [J].
Angermayr, M ;
Roidl, A ;
Bandlow, W .
MOLECULAR MICROBIOLOGY, 2002, 44 (02) :309-324
[8]  
Bachellerie JP, 2000, RIBOSOME: STRUCTURE, FUNCTION, ANTIBIOTICS, AND CELLULAR INTERACTIONS, P191
[9]   The RNA world of the nucleolus: Two major families of small RNAs defined by different box elements with related functions [J].
Balakin, AG ;
Smith, L ;
Fournier, MJ .
CELL, 1996, 86 (05) :823-834
[10]   The complete atomic structure of the large ribosomal subunit at 2.4 Å resolution [J].
Ban, N ;
Nissen, P ;
Hansen, J ;
Moore, PB ;
Steitz, TA .
SCIENCE, 2000, 289 (5481) :905-920
12345678910