Water is an efficient medium for Wittig reactions employing stabilized ylides and aldehydes

被引：75

作者：

Dambacher, J ^{[1
]}

Zhao, W ^{[1
]}

El-Batta, A ^{[1
]}

Anness, R ^{[1
]}

Jiang, CC ^{[1
]}

Bergdahl, M ^{[1
]}

机构：

[1] San Diego State Univ, Dept Biochem & Chem, San Diego, CA 92182 USA

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 26期

关键词：

enoate; enone; green chemistry; ylides; Wittig reaction;

D O I：

10.1016/j.tetlet.2005.04.105

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Water is demonstrated to be an excellent medium for the Wittig reaction employing stabilized ylides and aldehydes. Although the solubility in water appears to be an unimportant characteristic in achieving good chemical yields and E/Z-ratios, the rate of Wittig reactions in water is unexpectedly accelerated. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：4473 / 4477

页数：5

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