Microalgae-based Pharmaceuticals and Nutraceuticals: An Emerging Field with Immense Market Potential

被引：65

作者：

Jha, Durga ^{[1
]}

Jain, Vishakha ^{[1
]}

Sharma, Brinda ^{[1
]}

Kant, Anil ^{[1
]}

Garlapati, Vijay Kumar ^{[1
]}

机构：

[1] Jaypee Univ Informat Technol, Dept Biotechnol & Bioinformat, Waknaghat 173234, Himachal Prades, India

来源：

CHEMBIOENG REVIEWS | 2017年 / 4卷 / 04期

关键词：

Nutraceuticals; Metabolic engineering; Microalgae; Pharmaceuticals; Production technologies; PHYTOENE DESATURASE GENE; CHLAMYDOMONAS-REINHARDTII; CHLORELLA-ZOFINGIENSIS; HAEMATOCOCCUS-PLUVIALIS; FATTY-ACID; SULFATED EXOPOLYSACCHARIDE; MIXOTROPHIC CULTIVATION; BIOLOGICAL-ACTIVITIES; DOCOSAHEXAENOIC ACID; BIODIESEL PRODUCTION;

D O I：

10.1002/cben.201600023

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Microalgae are one of the renewable sources for pharmaceutical compounds as well as biofuels. The microalgae sector is growing rapidly due to the scarcity of substrate sources, more yields, and the GRAS (generally recognized as safe) status of compounds associated with microalgae. Due to this GRAS status, the algal products are beneficial not only for the pharmaceutical but also for the food industry. In this review, insights into the different process aspects and obstacles of pharmaceutical and nutraceutical compounds derived from microalgae on large-scale are discussed. Various culture production methods like photoautotrophic, heterotrophic, and mixotrophic processes have been included and recent advances in metabolic strategies for upgrading the microalgal technology for pharmaceutical and nutraceutical compounds are highlighted as well as the prospects in the field presented. Overall, this review discusses the question, how microalgae can be a great advantage for the pharmaceutical and nutraceutical industry.

引用

页码：257 / 271

页数：15

共 129 条

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