REPLY TO TRAN ET AL.: Dimeric KRAS protein-protein interaction stabilizers

被引：13

作者：

Kessler, Dirk ^{[1
]}

Gollner, Andreas ^{[1
]}

Gmachl, Michael ^{[1
]}

Mantoulidis, Andreas ^{[1
]}

Martin, Laetitia J. ^{[1
]}

Zoephel, Andreas ^{[1
]}

Mayer, Moriz ^{[1
]}

Covini, David ^{[1
]}

Fischer, Silke ^{[1
]}

Gerstberger, Thomas ^{[1
]}

Gmaschitz, Teresa ^{[1
]}

Goodwin, Craig ^{[2
]}

Greb, Peter ^{[1
]}

Haering, Daniela ^{[1
]}

Hela, Wolfgang ^{[1
]}

Hoffmann, Johann ^{[1
]}

Karolyi-Oezguer, Jale ^{[1
]}

Knesl, Petr ^{[1
]}

Kornigg, Stefan ^{[1
]}

Koegl, Manfred ^{[1
]}

Kousek, Roland ^{[1
]}

Lamarre, Lyne ^{[1
]}

Moser, Franziska ^{[3
]}

Munico-Martinez, Silvia ^{[1
]}

Peinsipp, Christoph ^{[1
]}

Phan, Jason ^{[2
]}

Rinnenthal, Joerg ^{[1
]}

Sai, Jiqing ^{[2
]}

Salamon, Christian ^{[1
]}

Scherbantin, Yvonne ^{[1
]}

Schipany, Katharina ^{[1
]}

Schnitzer, Renate ^{[1
]}

Schrenk, Andreas ^{[1
]}

Sharps, Bernadette ^{[1
]}

Siszler, Gabriella ^{[1
]}

Sun, Qi ^{[2
]}

Waterson, Alex ^{[4
,5
]}

Wolkerstorfer, Bernhard ^{[1
]}

Zeeb, Markus ^{[3
]}

Pearson, Mark ^{[1
]}

Fesik, Stephen W. ^{[2
,4
,5
]}

McConnell, Darryl B. ^{[1
]}

机构：

[1] Boehringer Ingelheim RCV GmbH & Co KG, Discovery Res, A-1120 Vienna, Austria

[2] Vanderbilt Univ, Sch Med, Dept Biochem, Nashville, TN 37235 USA

[3] Boehringer Ingelheim Pharma GmbH & Co KG, Discovery Res, D-88397 Biberach An Der Riss, Germany

[4] Vanderbilt Univ, Sch Med, Dept Pharmacol, Nashville, TN 37235 USA

[5] Vanderbilt Univ, Dept Chem, Nashville, TN 37235 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2020年 / 117卷 / 07期

关键词：

D O I：

10.1073/pnas.1921236117

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：3365 / 3367

页数：3

共 5 条

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Martin, Laetitia J. ;

Zoephel, Andreas ;

Mayer, Moriz ;

Gollner, Andreas ;

Covini, David ;

Fischer, Silke ;

Gerstberger, Thomas ;

Gmaschitz, Teresa ;

Goodwin, Craig ;

Greb, Peter ;

Haring, Daniela ;

Hela, Wolfgang ;

Hoffmann, Johann ;

Karolyi-Oezguer, Jale ;

Knesi, Petr ;

Kornigg, Stefan ;

Koegl, Manfred ;

Kousek, Roland ;

Lamarre, Lyne ;

Moser, Franziska ;

Munico-Martinez, Silvia ;

Peinsipp, Christoph ;

Phan, Jason ;

Rinnenthal, Joerg ;

Sai, Jiqing ;

Salamon, Christian ;

Scherbantin, Yvonne ;

Schipany, Katharina ;

Schnitzer, Renate ;

Schrenk, Andreas ;

Sharps, Bernadette ;

Siszler, Gabriella ;

Sun, Qi ;

Waterson, Alex ;

Wolkerstorfer, Bernhard ;

Zeeb, Markus ;

Pearson, Mark ;

Fesik, Stephen W. ;

McConnell, Darryl B. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (32) :15823-15829

[5] The small molecule BI-2852 induces a nonfunctional dimer of KRAS [J].

Tran, Timothy H. ;

Alexander, Patrick ;

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Balius, Trent E. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (07) :3363-3364

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