Thalidomide for de novo Crohn's disease after ileal pouch anal anastomosis for ulcerative colitis

被引：1

作者：

Dipasquale, Valeria ^{[1
]}

Tropeano, Angelo ^{[1
]}

Caime, Flavia ^{[1
]}

Romano, Claudio ^{[1
]}

机构：

[1] Univ Messina, Dept Human Pathol Adulthood & Childhood G Barresi, Unit Pediat Gastroenterol & Cyst Fibrosis, Messina, Italy

来源：

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS | 2020年 / 45卷 / 04期

关键词：

de novo Crohn's disease; ileal pouch anal anastomosis; paediatrics; thalidomide; PEDIATRIC-PATIENTS; OUTCOMES; MANAGEMENT; DIAGNOSIS; CHILDREN; SEROLOGY; THERAPY;

D O I：

10.1111/jcpt.13140

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

What is known and the objective De novo Crohn's disease (CD) is an increasingly reported diagnosis after ileal pouch anal anastomosis (IPAA). Currently, no consensus exists on the best treatment strategy. Case summary This report details the case of a 5-year-old child with early-onset ulcerative colitis (UC) who developed findings compatible with CD 12 months after IPAA. Thalidomide therapy led to clinical and endoscopic remission without side effects at 6 months. What is new and conclusion To our knowledge, this is the first report of thalidomide for treatment of de novo CD. Thalidomide therapy could be considered in patients with de novo CD, with similar indications of CD.

引用

页码：819 / 821

页数：3

共 18 条

[1] Fate of the pouch in 151 pediatric patients after ileal pouch anal anastomosis
Alexander, F
Sarigol, S
DiFiore, J
Stallion, A
Cotman, K
Clark, H
Lydzinski, B
Fazio, V
[J]. JOURNAL OF PEDIATRIC SURGERY, 2003, 38 (01) : 78 - 82
[2] [Anonymous], 2007, J PEDIAT GASTROENTER
[3] Management of Crohn's disease of the heoanal pouch with infliximab
Colombel, JF
Ricart, E
Loftus, EV
Tremaine, WJ
Young-Fadok, T
Dozois, EJ
Wolff, BG
Devine, R
Pemberton, JH
Sandborn, WJ
[J]. AMERICAN JOURNAL OF GASTROENTEROLOGY, 2003, 98 (10) : 2239 - 2244
[4] Thalidomide Use and Outcomes in Pediatric Patients With Crohn Disease Refractory to Infliximab and Adalimumab
Felipez, Lina M.
Gokhale, Ranjana
Tierney, Matthew P.
Kirschner, Barbara S.
[J]. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2012, 54 (01) : 28 - 33
[5] De Novo Crohn's Disease of the Pouch in Children Undergoing Ileal Pouch-Anal Anastomosis for Ulcerative Colitis
Jarchin, Lauren
Spencer, Elizabeth A.
Khaitov, Sergey
Greenstein, Alexander
Jossen, Jacqueline
Lai, Joanne
Dunkin, David
Pittman, Nanci
Benkov, Keith
Dubinsky, Marla C.
[J]. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2019, 69 (04) : 455 - 460
[6] How Secure Is the Diagnosis of Ulcerative Colitis in Children, Even After Colectomy?
Jones, Ian
Ramani, Pramila
Spray, Christine
Cusick, Eleri
[J]. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2018, 66 (01) : 69 - 72
[7] Laffitte Emmanuel, 2004, Expert Opin Drug Saf, V3, P47, DOI 10.1517/14740338.3.1.47
[8] Effect of Thalidomide on Clinical Remission in Children and Adolescents With Refractory Crohn Disease A Randomized Clinical Trial
Lazzerini, Marzia
Martelossi, Stefano
Magazzu, Giuseppe
Pellegrino, Salvatore
Lucanto, Maria Cristina
Barabino, Arrigo
Calvi, Angela
Arrigo, Serena
Lionetti, Paolo
Lorusso, Monica
Mangiantini, Francesca
Fontana, Massimo
Zuin, Giovanna
Palla, Gabriella
Maggiore, Giuseppe
Bramuzzo, Matteo
Pellegrin, Maria Chiara
Maschio, Massimo
Villanacci, Vincenzo
Manenti, Stefania
Decorti, Giuliana
De Iudicibus, Sara
Paparazzo, Rossella
Montico, Marcella
Ventura, Alessandro
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 310 (20): : 2164 - 2173
[9] Adalimumab therapy in Crohn's disease of the ileal pouch
Li, Yue
Lopez, Rocio
Queener, Elaine
Shen, Bo
[J]. INFLAMMATORY BOWEL DISEASES, 2012, 18 (12) : 2232 - 2239
[10] Family history and serology predict Crohn's disease after ileal pouch-anal anastomosis for ulcerative colitis
Melmed, Gil Y.
Fleshner, Phillip R.
Bardakcioglu, Ovunc
Ippoliti, Andrew
Vasiliauskas, Eric A.
Papadakis, Konstantinos A.
Dubinsky, Marla
Landers, Carol
Rotter, Jerome I.
Targan, Stephan R.
[J]. DISEASES OF THE COLON & RECTUM, 2008, 51 (01) : 100 - 108

← 1 2 →