Magnetic biosensor technologies for medical applications: a review

被引：169

作者：

Llandro, J. ^{[1
]}

Palfreyman, J. J. ^{[1
]}

Ionescu, A. ^{[1
]}

Barnes, C. H. W. ^{[1
]}

机构：

[1] Univ Cambridge, Cavendish Lab, Cambridge CB3 0HE, England

来源：

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING | 2010年 / 48卷 / 10期

基金：

英国工程与自然科学研究理事会;

关键词：

Magnetic biosensors; Magnetic nanoparticles; Functionalisation; Biomedicine; SELF-ASSEMBLED MONOLAYERS; SPIN-VALVE SENSORS; GIANT MAGNETORESISTANCE; MOLECULAR RECOGNITION; BIOMOLECULAR LABELS; SENSITIVE ELEMENT; ROOM-TEMPERATURE; HALL SENSORS; DNA; NANOPARTICLES;

D O I：

10.1007/s11517-010-0649-3

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

In this review we discuss conventional methods of performing biological assays and molecular identification and highlight their advantages and limitations. An alternative approach based on magnetic nanotechnology is then presented. Firstly, magnetic carriers are introduced and their biocompatibility and functionalisation discussed, with spotlights on functionalisation via self assembled monolayers and on methods of reducing nonspecific binding. In addition an introduction is provided to the basic physical concepts behind the various types of sensors used to detect magnetic labels. Finally, progress in the field of magnetic biosensors and the outlook for the future are discussed.

引用

页码：977 / 998

页数：22

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