Maternal Hepatitis B or Hepatitis C Virus Carrier Status is Not a Risk Factor for Long-Term Oncologic Morbidity of the Offspring: A Population-Based Cohort Study
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Abu-Freha, Naim
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Soroka Univ, Med Ctr, Inst Gastroenterol & Hepatol, POB 151, IL-84101 Beer Sheva, Israel
Ben Gurion Univ Negev, Fac Hlth Sci, Beer Sheva, IsraelSoroka Univ, Med Ctr, Inst Gastroenterol & Hepatol, POB 151, IL-84101 Beer Sheva, Israel
Abu-Freha, Naim
[1
,2
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Wainstock, Tamar
[3
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Poupko, Liat
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Ben Gurion Univ Negev, Med Sch Int Hlth, Beer Sheva, IsraelSoroka Univ, Med Ctr, Inst Gastroenterol & Hepatol, POB 151, IL-84101 Beer Sheva, Israel
Poupko, Liat
[4
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Sheiner, Eyal
[5
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[1] Soroka Univ, Med Ctr, Inst Gastroenterol & Hepatol, POB 151, IL-84101 Beer Sheva, Israel
[2] Ben Gurion Univ Negev, Fac Hlth Sci, Beer Sheva, Israel
[3] Ben Gurion Univ Negev, Fac Hlth Sci, Dept Publ Hlth, Beer Sheva, Israel
[4] Ben Gurion Univ Negev, Med Sch Int Hlth, Beer Sheva, Israel
[5] Ben Gurion Univ Negev, Soroka Univ, Dept Obstet & Gynecol, Med Ctr, Beer Sheva, Israel
We investigated whether maternal hepatitis B virus (HBV) or hepatitis C virus (HCV) carrier status increases the risk for long-term oncologic morbidity of their offspring up to the age of 18 years. A population-based cohort study was conducted, including all singleton deliveries between the years 1991 and 2014 at a tertiary medical center. Our study included: HBV carriers (n = 588), HCV carriers (n = 183) and non-carriers (n = 241,570. No significant differences regarding oncologic morbidity were found between offspring of HBV carriers (0.2%), HCV carriers (0%) and non-carriers (0.6%; p = 0.216, respectively). To conclude: maternal HBV or HCV carrier status is not a risk factor for long-term oncologic morbidity of the offspring.
机构:
Ctr Dis Control & Prevent, Div Viral Hepatitis, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA USAJohns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA
Groeger, Justina
Flaxman, Abraham D.
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Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USAJohns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA
Flaxman, Abraham D.
Wiersma, Steven T.
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WHO, Global Hepatitis Programme, CH-1211 Geneva, SwitzerlandJohns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA
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Childrens Hosp, Ctr Childhood Liver Dis, Div Gastroenterol, Boston, MA 02115 USAChildrens Hosp, Ctr Childhood Liver Dis, Div Gastroenterol, Boston, MA 02115 USA
机构:
Ctr Dis Control & Prevent, Div Viral Hepatitis, Natl Ctr HIV AIDS Viral Hepatitis STD & TB Preven, Atlanta, GA USAJohns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA
Groeger, Justina
Flaxman, Abraham D.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USAJohns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA
Flaxman, Abraham D.
Wiersma, Steven T.
论文数: 0引用数: 0
h-index: 0
机构:
WHO, Global Hepatitis Programme, CH-1211 Geneva, SwitzerlandJohns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA
机构:
Childrens Hosp, Ctr Childhood Liver Dis, Div Gastroenterol, Boston, MA 02115 USAChildrens Hosp, Ctr Childhood Liver Dis, Div Gastroenterol, Boston, MA 02115 USA