Species-, serogroup-, and serovar-specific epitopes are juxtaposed in variable sequence region 4 of the major outer membrane proteins of some Chlamydia trachomatis serovars

被引：13

作者：

Batteiger, BE ^{[1
]}

Lin, PM ^{[1
]}

Jones, RB ^{[1
]}

VanderPol, BJ ^{[1
]}

机构：

[1] INDIANA UNIV,SCH MED,DEPT MICROBIOL & IMMUNOL,INDIANAPOLIS,IN 46202

来源：

INFECTION AND IMMUNITY | 1996年 / 64卷 / 07期

关键词：

D O I：

10.1128/IAI.64.7.2839-2841.1996

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Synthetic peptides and marine monoclonal antibodies were used to map cross-reactive chlamydial epitopes. A species-specific epitope in the central region of variable sequence region 4 abuts the amino-terminal end of a B-serogroup-specific or F/G-serogroup-specific epitope, which in turn abuts known serovar-specific epitopes. The carboxyl-terminal portion of variable sequence region 4 (residues 297 to 314) comprises a region of end-to-end B-cell epitopes in some serovars of the B and F/G serogroups.

引用

页码：2839 / 2841

页数：3

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