Derivation of developmentally competent oocytes by in vitro culture of preantral follicles retrieved from aged mice

被引：5
作者：
Choi, Jung Kyu [1 ]
Ahn, Jong Il [2 ]
Park, Jong Heum [1 ,2 ]
Lim, Jeong Mook [1 ,2 ,3 ]
机构：
[1] Seoul Natl Univ, Dept Agr Biotechnol, Bldg 200,4223,Sillim 9 Dong, Seoul 151921, South Korea
[2] Seoul Natl Univ, WCU Biomodulat Program, Seoul 151921, South Korea
[3] Seoul Natl Univ, Canc Res Inst, Seoul 151921, South Korea
来源：
FERTILITY AND STERILITY | 2011年 / 95卷 / 04期
基金：
新加坡国家研究基金会;
关键词：
Aged mouse; preantral follicle; in vitro culture; follicle growth; IVF; embryo development; ESTABLISHMENT; CELLS;
D O I：
10.1016/j.fertnstert.2010.12.062
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Mature oocytes were derived from cultured preantral follicles retrieved from aged (63-67 weeks old) mice with decreased fecundity; IVF of the oocytes resulted in cleaving embryos. There was no difference in developmental competence of 4-cell embryos to the blastocyst stage between the adult and the aged groups, although general retardation of follicle development and oocyte maturation and development after IVF was detected. (Fertil Steril (R) 2011; 95: 1487-9. (C) 2011 by American Society for Reproductive Medicine.)
引用
收藏
页码：1487 / 1489
页数：3
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