Invasive ocular fungal infection by Scedosporium apiospermum in an immunocompromised patient

被引：0

作者：

Palma-Fernandez, Renato ^{[1
]}

Montecinos-Astorga, Alba ^{[2
,6
]}

Fica, Alberto ^{[1
,7
]}

Godoy-Martinez, Patricio ^{[3
]}

Aguilera, Ivan ^{[4
]}

Pinar-Pacheco, Cristobal ^{[5
]}

机构：

[1] Hosp Base Valdivia, Subdept Med, Valdivia, Chile

[2] Hosp Base Valdivia, Serv Oftalmol, Valdivia, Chile

[3] Univ Austral Chile, Inst Microbiol Clin, Fac Med, Valdivia, Chile

[4] Hosp Base Valdivia, Subdept Anat Patol, Valdivia, Chile

[5] Hosp Villarrica, Villarrica, Region De La Ar, Chile

[6] Univ Austral Chile, Fac Med, Unidad Oftalmol, Inst Especialidades, Valdivia, Chile

[7] Univ Austral Chile, Fac Med, Inst Med, Valdivia, Chile

来源：

REVISTA CHILENA DE INFECTOLOGIA | 2021年 / 38卷 / 04期

关键词：

Scedosporium apiospermum; conjunctivitis; panuveitis; neutropenia; voriconazole; VORICONAZOLE; ENDOPHTHALMITIS; MANAGEMENT; DIAGNOSIS; FUSARIUM;

D O I：

暂无

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report a case of invasive fungal infection with necrotizing conjunctivitis, scleritis and unilateral panuveitis caused by Scedosporium apiospermum in a 78-year-old woman that developed neutropenia by drugs indicated for rheumatoid arthritis. The etiological diagnosis was confirmed by mycological culture of an ocular secretion with the support of MALDI-TON-TOF analysis and histopathological findings. The treatment involved surgical debridements together with topical solution and systemic therapy with voriconazole and steroids with a favorable evolution after 2 months of treatment. A relapse required a second therapeutic course for an additional 12 months with improvement and eradication of the agent. Fungal conjunctivitis due to S. apiospermuni is a rare event associated with inununosuppressed patients. Its treatment involves surgical debridements and prolonged antifungal therapy.

引用

页码：568 / 573

页数：6

共 24 条

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