Botulinum Toxin-Associated Prolonged Remission of Idiopathic Cervical Dystonia

被引：0

作者：

Saranza, Gerard ^{[1
,2
,3
]}

Chen, Kai-Hsiang Stanley ^{[1
,2
,4
]}

Ganos, Christos ^{[5
]}

Kalia, Lorraine V. ^{[1
,2
,6
]}

Chen, Robert ^{[1
,2
,6
]}

Lang, Anthony E. ^{[1
,2
,6
]}

机构：

[1] Toronto Western Hosp, Edmond J Safra Program Parkinsons Dis, Toronto, ON, Canada

[2] Toronto Western Hosp, Morton & Gloria Shulman Movement Disorders Clin, Toronto, ON, Canada

[3] Chong Hua Hosp, Dept Med, Sect Neurol, Cebu, Philippines

[4] Natl Taiwan Univ Hosp, Hsin Chu Branch, Dept Neurol, Hsinchu, Taiwan

[5] Charite, Dept Neurol, Berlin, Germany

[6] Univ Toronto, Dept Med, Div Neurol, Toronto, ON, Canada

来源：

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES | 2021年 / 48卷 / 06期

关键词：

Botulinum toxin; Remission; Cervical dystonia; Dystonia; Relapse;

D O I：

10.1017/cjn.2020.280

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Prolonged remission of dystonia occurs rarely; however, well-documented cases are lacking. We report the clinical characteristics and course of four patients with botulinum toxin (BoNT)-associated prolonged remission of idiopathic cervical dystonia. Mean age at onset was 40 years. All had a relatively short duration of symptoms (mean 10.3 months), and with remission occurring after <= 3 treatments with BoNT. At last examination, the remission duration was 2-5 years. In the two cases that subsequently relapsed after 4-5 years, there was an altered phenomenology and worsened severity than at the onset. Recognizing this rare phenomenon has valuable clinical implications.

引用

页码：864 / 868

页数：5

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