Resveratrol effects in oral cancer cells: a comprehensive review

被引：16
作者：
Almeida, Tamires Cunha [1 ]
da Silva, Glenda Nicioli [1 ]
de Souza, Daniel Vitor [2 ]
de Moraes Malinverni, Andrea Cristina [3 ]
Aguiar Jr, Odair [2 ]
Estadella, Debora [2 ]
Ribeiro, Daniel Araki [2 ]
机构：
[1] Univ Fed Ouro Preto, Lab Clin Res, Ouro Preto, MG, Brazil
[2] Univ Fed Sao Paulo, Inst Hlth & Soc, Dept Biosci, UNIFESP, Rua Silva Jardim,136,Room 332, BR-11050020 Santos, SP, Brazil
[3] Univ Fed Sao Paulo, Paulista Med Sch, Dept Pathol, UNIFESP, Sao Paulo, SP, Brazil
来源：
MEDICAL ONCOLOGY | 2021年 / 38卷 / 08期
关键词：
Resveratrol; Oral cancer; In vitro; In vivo; TRANS-RESVERATROL; CARCINOMA; EXPRESSION; APOPTOSIS; RISK; HEAD; METASTASIS; CURCUMIN; GROWTH; SAFETY;
D O I：
10.1007/s12032-021-01548-0
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Oral cancer is a very common tumor worldwide with high incidence and mortality. The treatment of oral cancer involves surgery, radio- and chemotherapy; however, high failure rates and toxicity are noticed. Thus, the search of new drugs aiming a more effective treatment is welcomed. Natural products present chemopreventive and anti-cancer effects. Resveratrol is a naturally occurring antioxidant that contains several health benefits, including anti-inflammatory and antiproliferative activities. This review discusses the different action mechanisms of resveratrol related in the in vitro and in vivo studies using models of oral cancer.
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页数：10
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