Early continence recovery after open radical prostatectomy with restoration of the posterior aspect of the rhabdosphincter

被引:165
作者
Rocco, Francesco
Carmignani, Luca
Acquati, Pietro
Gadda, Franco
Dell'Orto, Paolo
Rocco, Bernardo
Casellato, Stefano
Gazzano, Giacomo
Consonni, Dario
机构
[1] Univ Milan, Clin Urol 1, Fdn Osped Maggiore Policlin, I-20122 Milan, Italy
[2] Ist Europeo Oncol, Urol Unit, Milan, Italy
[3] Univ Milan, Div Pathol, Dept Med Surg & Dent Sci, AOS Paolo, Milan, Italy
[4] Fdn Osped Maggiore Policlin, Dipartimento Epidemiol, I-20122 Milan, Italy
关键词
continence; prostate cancer; radical retropubic prostatectomy; rhabdosphincter;
D O I
10.1016/j.eururo.2007.01.109
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Objectives: We believe early incontinence after radical retropubic prostatectomy (RRP) is mainly due to the shortening of the sphincter's anatomic and functional length as a result of caudal retraction of the urethral sphincteric complex and disruption of the posterior median fibrous raphe. We illustrate a technique of anatomic and functional reconstruction of the rhabdosphincter (RS) aimed at achieving early continence recovery after RRP. our modification to the Walsh RRP avoids caudal retraction of the urethrosphincteric complex and reconstructs the posterior fibrous raphe. Methods: Prior to completion of the vesicourethral anastomosis, the posterior fibrous tissues of the sphincter are joined to the residual Denonvilliers fascia on the posterior bladder wall 1-2 cm cephalad and dorsally to the new bladder neck. The study end point was assessment of early and long-term continence rate. Modified RRP (group 1: 250 patients) was compared with unmodified RRP (historical group 2: 50 patients). A crude comparison of treatment effect was assessed by using Pearson chi-square. Multiple logistic regression was used to assess treatment efficacy at discharge, 1, 3, and 12 mo, while taking into account age, pathologic stage, and Gleason score. Continence was defined as 0-1 pad per day. Results: Patients in group 1 achieved significantly better continence at discharge (62.4% vs. 14.0%), 1 mo (74.0% vs. 30%), and 3 mo of follow-up (85.2% vs. 46%); long-term recovery was similar in the two treatment groups (94% vs. 90%). Conclusions: The technical modification that we proposed achieved a substantial and significant reduction in time to continence with no adverse effects. (C) 2007 Published by Elsevier B.V. on behalf of European Association of Urology.
引用
收藏
页码:376 / 383
页数:8
相关论文
共 27 条
[1]   Successful transfer of open surgical skills to a laparoscopic environment using a robotic interface: Initial experience with laparoscopic radical prostatectomy [J].
Ahlering, TE ;
Skarecky, D ;
Lee, D ;
Clayman, RV .
JOURNAL OF UROLOGY, 2003, 170 (05) :1738-1741
[2]  
[Anonymous], 2005, STAT STAT SOFTW REL
[3]  
[Anonymous], 1992, CAMBELLS UROLOGY
[4]  
Avery K., 2001, Neurourology and Urodynamics, V20, P510
[5]   Nerve sparing open radical retropubic prostatectomy - Does it have an impact on urinary continence? [J].
Burkhard, Fiona C. ;
Kessler, Thomas M. ;
Fleischmann, Achim ;
Thalmann, George N. ;
Schumacher, Martin ;
Studer, Urs E. .
JOURNAL OF UROLOGY, 2006, 176 (01) :189-195
[6]   In situ anatomical study of the male urethral sphincteric complex: Relevance to continence preservation following major pelvic surgery [J].
Burnett, AL ;
Mostwin, JL .
JOURNAL OF UROLOGY, 1998, 160 (04) :1301-1306
[7]   Potency, continence and complication rates in 1,870 consecutive radical retropubic prostatectomies [J].
Catalona, WJ ;
Carvalhal, GF ;
Mager, DE ;
Smith, DS .
JOURNAL OF UROLOGY, 1999, 162 (02) :433-438
[8]  
EASTHAM JA, 2000, COMPREHENSIVE TXB GE, P722
[9]   Oncologic outcome and continence recovery after laparoscopic radical prostatectomy: 3 years' follow-up in a "second generation center" [J].
Galli, S ;
Simonato, A ;
Bozzola, A ;
Gregori, A ;
Lissiani, A ;
Scaburri, A ;
Gaboardi, F .
EUROPEAN UROLOGY, 2006, 49 (05) :859-865
[10]   Comparison of operative and functional outcomes of laparoscopic radical prostatectomy and radical retropubic prostatectomy: Single surgeon experience [J].
Ghavamian, Reza ;
Knoll, Abraham ;
Boczko, Judd ;
Melman, Arnold .
UROLOGY, 2006, 67 (06) :1241-1246