N-Cyanomethyl-β-chloroamines:: a convenient source of aziridinium ions

被引：23
作者：
Couty, F [1 ]
Evano, G [1 ]
Prim, D [1 ]
机构：
[1] Univ Versailles, CNRS, UMR 8086, SIRCOB, F-78035 Versailles, France
来源：
TETRAHEDRON LETTERS | 2005年 / 46卷 / 13期
关键词：
1,2-aminoethers; 1,2-diamines;
D O I：
10.1016/j.tetlet.2005.02.016
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
N-Cyanomethyl-beta-chloroamines smoothly react with a range of alcohols or amines to give regio- and stereoselectively 1,2-aminoethers or 1,2-diamines. The reaction proceeds through the formation of an intermediate aziridinium ion. The N-cyanomethyl group can then be cleaved easily. (c) 2005 Elsevier Ltd. All rights reserved.
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收藏
页码：2253 / 2257
页数：5
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