IgG4-related disease in a non-healing gastric ulcer: case report

被引：0

作者：

Moyer, Amanda B. ^{[1
]}

Schwartz, Mary R. ^{[1
]}

Lim, Sherry ^{[2
]}

Tompson, Matthew L. ^{[3
]}

Ro, Jae Y. ^{[1
]}

机构：

[1] Cornell Univ, Weill Med Coll, Houston Methodist Hosp, Dept Pathol & Genom Med, 6565 Fannin St, Houston, TX 77030 USA

[2] Cornell Univ, Weill Med Coll, Houston Methodist Hosp, Dept Surg, Houston, TX 77030 USA

[3] Cornell Univ, Weill Med Coll, Houston Methodist Hosp, Dept Gastroenterol, Houston, TX 77030 USA

来源：

INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY | 2016年 / 9卷 / 06期

关键词：

IgG4; gastric ulcer; PLASMA-CELL INFILTRATION; PANCREATITIS;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report a 28-year-old woman with a refractory gastric ulcer in the absence of Helicobacter pylori infection and autoimmune pancreatitis. Histologic examination of the gastric ulcer demonstrated abundant IgG4 positive plasma cells populating a lymphoplasmacytic infiltrate with associated sclerosis. Our case suggests that treatment-refractory peptic ulcer may be related to IgG4-related inflammation. When a biopsy performed to evaluate a refractory ulcer reveals abundant plasma cells and sclerotic fibrosis, an immunohistochemical stain for IgG4 and serum IgG4 measurement might be considered.

引用

页码：6588 / 6591

页数：4

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