Optimal Release Timing of Drain Clamping to Reduce Postoperative Bleeding after Total Knee Arthroplasty with Intraarticular Injection of Tranexamic Acid

被引:3
作者
Kim, Myung-Ku [1 ]
Ko, Sang-Hyun [1 ]
Nam, Yoon-Cheol [1 ]
Jeon, Yoon-Sang [1 ]
Kwon, Dae-Gyu [1 ]
Ryu, Dong-Jin [1 ]
机构
[1] Inha Univ Hosp, Dept Orthopaed Surg, Incheon 22332, South Korea
来源
MEDICINA-LITHUANIA | 2022年 / 58卷 / 09期
关键词
total knee arthroplasty; tranexamic acid; clamping time; transfusion; estimated blood loss; BLOOD-LOSS; TOTAL HIP; TRANSFUSION; REPLACEMENT; EFFICACY; SAFETY; VOLUME; RISK;
D O I
10.3390/medicina58091226
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and Objectives: Intraarticular injection of tranexamic acid (IA-TXA) plus drain-clamping is a preferred method of reducing bleeding after total knee arthroplasty (TKA). However, no consensus has been reached regarding the timing of the clamping. The purpose of this study was to determine the optimum duration of drain-clamping after TKA with IA-TXA. Materials and Methods: We retrospectively reviewed 151 patients that underwent unilateral TKA with IA-TXA plus drain-clamping for 30 min, 2 h, or 3 h. The total drained volume was reviewed as the primary outcome, and hematocrit (Hct) reductions, estimated blood loss (EBL), transfusion rates, and wound complications were reviewed as secondary outcomes. Results: The mean total drained volume, Hct reduction, and EBL were significantly less in the 3 h group than in the 30 min group. Between the 2 h and 3 h groups, there was no statistical difference in the mean total drained volume, Hct reduction, or EBL. The proportion of patients who drained lesser than 300 mL was high in the 3 h group. No significant intergroup difference was observed for transfusion volume, transfusion rate, and wound related complications. Conclusions: In comparison of the IA-TXA plus drain-clamping after TKA, there was no difference in EBL between the 2 h group and the 3 h group, but the amount of drainage volume was small in the 3 h group.
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页数:8
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