Is there a role for physical activity in preventing cognitive decline in people with mild cognitive impairment?

被引:35
作者
Barber, Sally E. [1 ]
Clegg, Andrew P. [1 ]
Young, John B. [1 ]
机构
[1] Bradford Inst Hlth Res, Acad Unit Elderly Care & Rehabil, Bradford BD9 6RJ, W Yorkshire, England
关键词
dementia; prevention; exercise therapy; cognition; ageing; OLDER-ADULTS; ALZHEIMER-DISEASE; AEROBIC FITNESS; EXERCISE; RISK; DEMENTIA; METAANALYSIS; WALKING;
D O I
10.1093/ageing/afr138
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Mild cognitive impairment (MCI) is a common clinical syndrome that identifies people at high risk of developing dementia. Although treatments for MCI are currently unavailable, preliminary evidence has identified potential neuro-protective effects of physical activity, which may lead to improved outcomes. However, there is uncertainty regarding the effectiveness, feasibility and acceptability of this treatment strategy. These uncertainties require further investigation before physical activity interventions can be recommended for routine care.
引用
收藏
页码:5 / 8
页数:4
相关论文
共 26 条
[1]   Is physical activity a potential preventive factor for vascular dementia? A systematic review [J].
Aarsland, Dag ;
Sardahaee, Farzaneh S. ;
Anderssen, Sigmund ;
Ballard, Clive .
AGING & MENTAL HEALTH, 2010, 14 (04) :386-395
[2]   Effects of Aerobic Exercise on Mild Cognitive Impairment A Controlled Trial [J].
Baker, Laura D. ;
Frank, Laura L. ;
Foster-Schubert, Karen ;
Green, Pattie S. ;
Wilkinson, Charles W. ;
McTiernan, Anne ;
Plymate, Stephen R. ;
Fishel, Mark A. ;
Watson, G. Stennis ;
Cholerton, Brenna A. ;
Duncan, Glen E. ;
Mehta, Pankaj D. ;
Craft, Suzanne .
ARCHIVES OF NEUROLOGY, 2010, 67 (01) :71-79
[3]   Risk of dementia in diabetes mellitus: a systematic review [J].
Biessels, GJ ;
Staekenborg, S ;
Brunner, E ;
Brayne, C ;
Scheltens, P .
LANCET NEUROLOGY, 2006, 5 (01) :64-74
[4]  
CASPERSEN CJ, 1985, PUBLIC HEALTH REP, V100, P126
[5]  
Colcombe SJ, 2003, J GERONTOL A-BIOL, V58, P176
[6]   Physical training in patients with chronic heart failure enhances the expression of genes encoding antioxidative enzymes [J].
Ennezat, PV ;
Malendowicz, SL ;
Testa, M ;
Colombo, PC ;
Cohen-Solal, A ;
Evans, T ;
LeJemtel, TH .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2001, 38 (01) :194-198
[7]  
Geda YE, 2010, ARCH NEUROL-CHICAGO, V67, P80, DOI 10.1001/archneurol.2009.297
[8]   Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence [J].
Hamer, M. ;
Chida, Y. .
PSYCHOLOGICAL MEDICINE, 2009, 39 (01) :3-11
[9]   Exercise protects the cardiovascular system: effects beyond traditional risk factors [J].
Joyner, Michael J. ;
Green, Daniel J. .
JOURNAL OF PHYSIOLOGY-LONDON, 2009, 587 (23) :5551-5558
[10]  
Knapp M., 2007, DEMENTIA UK