Functionalisation of mesoporous silica nanoparticles with 3-isocynatopropyltrichlorosilane

被引：2
作者：
El Malti, Wassim [1 ]
Mongin, Olivier [2 ]
Blanchard-Desce, Mireille [2 ]
Raehm, Laurence [1 ]
Durand, Jean-Olivier [1 ]
机构：
[1] Univ Montpellier 2, Inst Charles Gerhardt Montpellier, CNRS, UMR 5253, F-34095 Montpellier 5, France
[2] Univ Rennes 1, CNRS, UMR 6510, F-35042 Rennes, France
来源：
COMPTES RENDUS CHIMIE | 2011年 / 14卷 / 12期
关键词：
Isocyanates; Trichlorosilanes; Mesoporous Silica Nanoparticles; Amines; Two-photon; RELEASE DRUG-DELIVERY; SYSTEM; UREA;
D O I：
10.1016/j.crci.2011.09.008
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The functionalisation of Mesoporous Silica Nanoparticles (MSN) with the isocyanate group was carried out. The excellent reactivity of 3-isocynanatopropyltrichlorosilane allowed its grafting on the surface of MSN in mild conditions. Further reaction with different nucleophiles bearing primary amino groups led to the formation of a urea linkage and thus the covalent grafting of the nucleophiles to the MSN surface. (C) 2011 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：1055 / 1058
页数：4
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