Chitosan-g-PMMA/Kaolin Bionanocomposites for Use in Bioadhesive Bone-Cement Implants

被引:4
作者
Pradhan, Arun Kumar [1 ,2 ]
Sahoo, Prafulla Kumar [1 ]
Rana, Pradeep Kumar [2 ]
机构
[1] Utkal Univ, Dept Chem, Bhubaneswar 751004, Orissa, India
[2] Maharashtra Inst Technol, Plast & Polymer Engn Dept, Aurangabad 431005, Maharashtra, India
关键词
Chitosan; bone cement; bionanocomposite; bioadhesive; REGENERATIVE MEDICINE; TISSUE; VERTEBROPLASTY; BIODEGRADATION; STRENGTH; POROSITY;
D O I
10.7569/JRM.2017.634129
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Chitosan grafted with poly(methyl-methacrylate) (PMMA) and adsorbed with kaolin functionalized as bioadhesive was prepared via emulsion polymerization technique and physiochemically characterized as a bone-graft substitute. The so prepared grafted bioactive bone cement (BBC) bionanocomposites (BNCs), chitosan-g-PMMA/kaolin, was characterized by Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD) analysis, field-emission scanning electron microscopy (FESEM) and thermogravimetric analysis (TGA). The water uptake, retention ability and the nanosize particle arrangement in the polymeric BBC-BNCs were studied along with the mechanical and biodegradation properties. These preliminary investigations of the BNCs will open the door for their use in bioadhesive bone-cement implants in the future.
引用
收藏
页码:371 / 379
页数:9
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