The blessings and curses of C57BL/6 substrains in mouse genetic studies

被引：91

作者：

Bryant, Camron D. ^{[1
]}

机构：

[1] Univ Chicago, Dept Human Genet, Chicago, IL 60637 USA

来源：

ANIMAL MODELS: THEIR VALUE IN PREDICTING DRUG EFFICACY AND TOXICITY | 2011年 / 1245卷

关键词：

B6; inbred; KOMP; next-generation sequencing; QTL mapping;

D O I：

10.1111/j.1749-6632.2011.06325.x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Phenotypic and genetic differences among C57BL/6 substrains are accumulating. Investigators must address these differences to improve the quality of their studies.

引用

页码：31 / 33

页数：3

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