Effects of Copper Oxide Nanoparticles on Tissue Accumulation and Antioxidant Enzymes of Galleria mellonella L.

被引：38

作者：

Tuncsoy, Benay Sezer ^{[1
]}

Tuncsoy, Mustafa ^{[1
]}

Gomes, Tania ^{[2
]}

Sousa, Vania ^{[3
]}

Teixeira, Margarida Ribau ^{[3
]}

Bebianno, Maria Joao ^{[4
]}

Ozalp, Pinar ^{[1
]}

机构：

[1] Cukurova Univ, Dept Biol, Fac Sci & Letters, TR-01330 Adana, Turkey

[2] Norwegian Inst Water Res NIVA, Gaustadalleen 21, N-0349 Oslo, Norway

[3] Univ Algarve, CENSE, Fac Sci & Technol, Campus Gambelas, P-8005139 Faro, Portugal

[4] Univ Algarve, CIMA, Fac Sci & Technol, Campus Gambelas, P-8005139 Faro, Portugal

来源：

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY | 2019年 / 102卷 / 03期

关键词：

Acetylcholinesterase; Antioxidant enzymes; Copper oxide nanoparticles; Galleria mellonella; Glutathione-s-transferase; GLUTATHIONE-S-TRANSFERASE; ENGINEERED NANOPARTICLES; SILVER NANOPARTICLES; ZNO NANOMATERIALS; OXIDATIVE STRESS; DAPHNIA-MAGNA; EXPOSURE; MUSSEL; TOXICITY; BIOMARKERS;

D O I：

10.1007/s00128-018-2529-8

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Effects of copper oxide nanoparticles (CuO NPs) were investigated in the midgut and fat body of Galleria mellonella. Fourth instar larvae were exposed to 10 mu g Cu/L of CuO until becoming last instar larvae, and catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione-s-transferase (GST) and acetylcholinesterase (AChE) and metal accumulation were evaluated. Copper accumulation was observed in midgut and fat body tissues of G. mellonella larvae exposed to CuO NPs. CuO NPs increased CAT activities in midgut and fat body, while SOD activities were decreased. CuO NPs exhibited significant increases in GST activity in fat body, while no significant differences were observed in the midgut of G. mellonella larvae. AChE activity significantly decreased in the midgut of G. mellonella whereas there is no significant effect on fat body in CuO NPs exposed larvae. In overall, these findings demonstrate that tissue accumulation and oxidative stress that is countered by antioxidant enzymes occur when G. mellonella larvae exposed to environmental concentration of CuO nanoparticles.

引用

页码：341 / 346

页数：6

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