Efficient Synthesis of 4H-Pyran and Spiro-Oxindole Derivatives Based on Al2O3/V2O5 Nanocomposite as Catalyst

被引:7
作者
Hassani, H. [1 ]
Jahani, Z. [1 ]
Poor, H. H. [1 ]
机构
[1] Payame Noor Univ, Dept Chem, Tehran 193954697, Iran
关键词
Al2O3; V2O5; nano catalyst; 4H-pyran; spiro-oxindole; multicomponent; reaction; ONE-POT SYNTHESIS; MULTICOMPONENT REACTIONS; GREEN SYNTHESIS; PYRANS; ACID; ORGANOCATALYSIS; SPIROOXINDOLES; SPIROINDOLONES; PYRIMIDINES; ACCESS;
D O I
10.1134/S1070428020030197
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A simple and eco-friendly catalytic alternative has been proposed for one-pot three-component synthesis of 4H-pyrane and spiro-oxindole derivatives, as two important classes of potentially bioactive compounds, in the presence of a catalytic amount of Al2O3/V2O5 nanocomposite. Good to excellent yields and short reaction times were obtained for both series of Al2O3/V2O5-catalyzed reactions. In addition, the Al2O3/V2O5 nanocatalyst can be reused without appreciable loss of activity. The obtained results suggest prospects of using Al2O3/V2O5 nanocomposite as potent heterogeneous catalyst in other syntheses.
引用
收藏
页码:491 / 497
页数:7
相关论文
共 46 条
  • [1] Akbari A., 2012, INT J CHEMTECH RES, V4, P729
  • [2] A green one-pot multicomponent synthesis of 4H-pyrans and polysubstituted aniline derivatives of biological, pharmacological, and optical applications using silica nanoparticles as reusable catalyst
    Banerjee, Subhash
    Horn, Alissa
    Khatri, Hari
    Sereda, Grigoriy
    [J]. TETRAHEDRON LETTERS, 2011, 52 (16) : 1878 - 1881
  • [3] Nano crystalline ZnO catalyzed one pot multicomponent reaction for an easy access of fully decorated 4H-pyran scaffolds and its rearrangement to 2-pyridone nucleus in aqueous media
    Bhattacharyya, Pranabes
    Pradhan, Koyel
    Paul, Sanjay
    Das, Asish R.
    [J]. TETRAHEDRON LETTERS, 2012, 53 (35) : 4687 - 4691
  • [4] Synthesis, cytotoxic, and DNA binding studies of novel fluorinated condensed pyrano pyrazoles
    Bhavanarushi, S.
    Kanakaiah, V.
    Yakaiah, E.
    Saddanapu, V.
    Addlagatta, A.
    Rani, J. Vatsala
    [J]. MEDICINAL CHEMISTRY RESEARCH, 2013, 22 (05) : 2446 - 2454
  • [5] Amberlyst A21: A reusable solid catalyst for green synthesis of pyran annulated heterocycles at room temperature
    Bihani, Manisha
    Bora, Pranjal P.
    Bez, Ghanashyam
    Askari, Hassan
    [J]. COMPTES RENDUS CHIMIE, 2013, 16 (05) : 419 - 426
  • [6] High analgesic and anti-inflammatory in vivo activities of six new hybrids NSAIAs tetrahydropyran derivatives
    Capim, Saulo L.
    Goncalves, Gabriela M.
    dos Santos, Gabriela C. M.
    Marinho, Bruno G.
    Vasconcellos, Mario L. A. A.
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 21 (19) : 6003 - 6010
  • [7] Step-economic, efficient, ZnS nanoparticle-catalyzed synthesis of spirooxindole derivatives in aqueous medium via Knoevenagel condensation followed by Michael addition
    Dandia, Anshu
    Parewa, Vijay
    Jain, Anuj Kumar
    Rathore, Kuldeep S.
    [J]. GREEN CHEMISTRY, 2011, 13 (08) : 2135 - 2145
  • [8] The novel trisubstituted pyran derivative D-142 has triple monoamine reuptake inhibitory activity and exerts potent antidepressant-like activity in rodents
    Dutta, Aloke K.
    Gopishetty, Bhaskar
    Gogoi, Sanjib
    Ali, Solav
    Zhen, Juan
    Reith, Maarten
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2011, 671 (1-3) : 39 - 44
  • [9] Efficient and Expeditious Synthesis of Pyrano-pyrimidines, Multi-substituted γ-Pyrans, and Their Antioxidant Activity
    El-Bayouki, Khairy A. M.
    Basyouni, Wahid M.
    Khatab, Tamer K.
    El-Basyoni, Fakhry A.
    Hamed, Ahmed R.
    Mostafa, Eslam A.
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2014, 51 (01) : 106 - 115
  • [10] Organocatalysis in Synthesis: L-Proline as an Enantioselective Catalyst in the Synthesis of Pyrans and Thiopyrans
    Elnagdi, Noha M. Hilmy
    Al-Hokbany, Noura Saad
    [J]. MOLECULES, 2012, 17 (04): : 4300 - 4312