Characterization and Properties of TEMPO-oxidized Bacterial Cellulose-Hydroxypatite for Osseous Regeneration

TEMPO-oxidized bacterial cellulose (TBC)/hydroxypatite (HA) composites prepared by physical synthesis was characterized. And the porosity and protein adsorption was measured to evaluate the properties of the composites. Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) images demonstrated that HA formed with appearing the peak of PO43-. The contact angles significantly decreased after oxidation and physical blending. Meanwhile the surface energy of TBC-HA increased clearly compared with TBC. After blending, the porosity increased and the maximum was 86.8% in the weight ratio of 1. The protein adsorption performed better after oxidation. And the protein entrapment efficiency (EE) of TBC was 22%. Base on this work, the TBC-HA composites would be demonstrated the potential application for osseous regeneration.