Epidural Spinal Cord Stimulation: A Novel Therapy in the Treatment of Restless Legs Syndrome

被引:14
作者
Holland, Marshall T. [1 ]
Rettenmaier, Leigh A. [1 ]
Flouty, Oliver E. [1 ]
Thomsen, Teri R. [2 ]
Jerath, Nivedita U. [2 ]
Reddy, Chandan G. [1 ]
机构
[1] Univ Iowa, Iowa Carver Coll Med, Dept Neurosurg, Iowa City, IA 52242 USA
[2] Univ Iowa, Dept Neurol, Iowa Carver Coll Med, Iowa City, IA 52242 USA
关键词
Epidural; Failed back syndrome; Periodic limb movements; Restless legs syndrome; Spinal cord stimulation;
D O I
10.1016/j.wneu.2016.05.077
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BACKGROUND: We report a unique finding of a patient whose restless legs syndrome (RLS) symptoms abated after the placement of a spinal cord stimulator for chronic neuropathic pain. RLS is a common disorder, with many patients unable to find sufficient relief from their symptoms. CASE DESCRIPTION: A patient diagnosed with neuropathic pain who also suffered from RLS symptoms despite medication therapy underwent implantation of a spinal cord stimulator after a successful trial. This patient was interviewed formally about his RLS symptoms immediately before his procedure and at 6 weeks, 6 months, and 2.5 years after the procedure. The patient also completed the International Restless Legs Syndrome Scale questionnaire to objectively quantify the severity of his symptoms. Finally, the patient kept a 5-day journal detailing when the stimulator was in use. The patient reported subjective symptomatic improvement in his RLS symptoms with improved sleep quality and quantity, in addition to improvement in his back pain. The patient's score on the International Restless Legs Syndrome Scale improved after implantation from 33 to 0 on a 40-point scale. Moreover, when asked to keep a journal record of his stimulator use, the patient noted that he only used the stimulator before going to bed to help his RLS symptoms and no longer required any medication for his previous RLS symptoms. CONCLUSIONS: Epidural stimulation may be an additional, alternative, or novel therapy in the treatment of RLS.
引用
收藏
页码:582.e15 / 582.e18
页数:4
相关论文
共 17 条
[1]   Restless legs syndrome - A review of clinical and pathophysiologic features [J].
Allen, RP ;
Earley, CJ .
JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 2001, 18 (02) :128-147
[2]   Repetitive transcranial magnetic stimulation in restless legs syndrome: preliminary results [J].
Altunrende, Burcu ;
Yildiz, Serpil ;
Cevik, Ayse ;
Yildiz, Nebil .
NEUROLOGICAL SCIENCES, 2014, 35 (07) :1083-1088
[3]   Restless legs syndrome: update on pathogenesis [J].
Dauvilliers, Yves ;
Winkelmann, Juliane .
CURRENT OPINION IN PULMONARY MEDICINE, 2013, 19 (06) :594-600
[4]   Restless legs syndrome [J].
Earley, CJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (21) :2103-2109
[5]   Managing Chronic Pain With Spinal Cord Stimulation [J].
Epstein, Lawrence J. ;
Palmieri, Marco .
MOUNT SINAI JOURNAL OF MEDICINE, 2012, 79 (01) :123-132
[6]   Neural Mechanisms of Spinal Cord Stimulation [J].
Foreman, Robert D. ;
Linderoth, Bengt .
EMERGING HORIZONS IN NEUROMODULATION: NEW FRONTIERS IN BRAIN AND SPINE STIMULATION, 2012, 107 :87-119
[7]   The long-term treatment of restless legs syndrome/Willis-Ekbom disease: evidence-based guidelines and clinical consensus best practice guidance: a report from the International Restless Legs Syndrome Study Group [J].
Garcia-Borreguero, Diego ;
Kohnen, Ralf ;
Silber, Michael H. ;
Winkelman, John W. ;
Earley, Christopher J. ;
Hoegl, Birgit ;
Manconi, Mauro ;
Montplaisir, Jacques ;
Inoue, Yuichi ;
Allen, Richard P. .
SLEEP MEDICINE, 2013, 14 (07) :675-684
[8]   Effects of Transcutaneous Spinal Direct Current Stimulation in Idiopathic Restless Legs Patients [J].
Heide, A. C. ;
Winkler, T. ;
Helms, H. J. ;
Nitsche, M. A. ;
Trenkwalder, C. ;
Paulus, W. ;
Bachmann, C. G. .
BRAIN STIMULATION, 2014, 7 (05) :636-642
[9]   What treatment works best for restless legs syndrome? Meta-analyses of dopaminergic and non-dopaminergic medications [J].
Hornyak, Magdolna ;
Scholz, Hanna ;
Kohnen, Ralf ;
Bengel, Juergen ;
Kassubek, Jan ;
Trenkwalder, Claudia .
SLEEP MEDICINE REVIEWS, 2014, 18 (02) :153-164
[10]  
Manchikanti Laxmaiah, 2013, Pain Physician, V16, pS49