Polysaccharide-based electroconductive hydrogels: Structure, properties and biomedical applications

被引:43
作者
Yazdi, Mohsen Khodadadi [1 ,2 ]
Zarrintaj, Payam [3 ]
Khodadadi, Ali [4 ]
Arefi, Ahmad [5 ]
Seidi, Farzad [1 ,2 ]
Shokrani, Hanieh [1 ,2 ]
Saeb, Mohammad Reza [6 ]
Mozafari, Masoud [7 ,8 ]
机构
[1] Nanjing Forestry Univ, Int Innovat Ctr Forest Chem & Mat, Nanjing 210037, Peoples R China
[2] Nanjing Forestry Univ, Jiangsu Coinnovat Ctr Efficient Proc & Utilizat F, Nanjing 210037, Peoples R China
[3] Oklahoma State Univ, Sch Chem Engn, 420 Engn North, Stillwater, OK 74078 USA
[4] Gonabad Univ Med Sci, Sch Med, Dept Internal Med, Gonabad, Iran
[5] McMaster Univ, Dept Chem Engn, Hamilton, ON, Canada
[6] Gdansk Univ Technol, Fac Chem, Dept Polymer Technol, G Narutowicza 11-12, PL-80233 Gdansk, Poland
[7] Iran Univ Med Sci, Fac Adv Technol Med, Dept Tissue Engn & Regenerat Med, Tehran, Iran
[8] Univ Toronto, Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Toronto, ON, Canada
关键词
Polysaccharides; Agarose; Alginate; Chitosan; Cellulose; Dextran; Stimuli responsive; Electroconductive hydrogels; Tissue engineering; Flexible electronics; Drug delivery; Biomaterials; CONDUCTIVE INJECTABLE HYDROGELS; N-CARBOXYETHYL CHITOSAN; PHOTOTHERMAL THERAPY; WOUND DRESSINGS; ANTIBACTERIAL; BIOMATERIALS; ANTIOXIDANT; SCAFFOLD; MICROENVIRONMENT; NANOPARTICLES;
D O I
10.1016/j.carbpol.2021.118998
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Architecting an appropriate platform for biomedical applications requires setting a balance between simplicity and complexity. Polysaccharides (PSAs) play essential roles in our life in food resources, structural materials, and energy storage capacitors. Moreover, the diversity and abundance of PSAs have made them an indispensable part of food ingredients and cosmetics. PSA-based hydrogels have been extensively reviewed in biomedical applications. These hydrogels can be designed in different forms to show optimum performance. For instance, electroactive PSA-based hydrogels respond under an electric stimulus. Such performance can be served in stimulus drug release and determining cell fate. This review classifies and discusses the structure, properties, and applications of the most important polysaccharide-based electroactive hydrogels (agarose, alginate, chitosan, cellulose, and dextran) in medicine, focusing on their usage in tissue engineering, flexible electronics, and drug delivery applications.
引用
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页数:21
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