GUIDANCE DOCUMENT FOR THE PREHOSPITAL USE OF TRANEXAMIC ACID IN INJURED PATIENTS

被引：16

作者：

Fischer, Peter E. ^{[1
]}

Bulger, Eileen M. ^{[2
]}

Perina, Debra G. ^{[3
]}

Delbridge, Theodore R. ^{[4
]}

Gestring, Mark L. ^{[5
]}

Fallat, Mary E. ^{[6
]}

Shatz, David V. ^{[7
]}

Doucet, Jay ^{[8
]}

Levy, Michael ^{[9
]}

Stuke, Lance ^{[10
]}

Zietlow, Scott P. ^{[11
]}

Goodloe, Jeffrey M. ^{[12
]}

VanderKolk, Wayne E. ^{[13
]}

Fox, Adam D. ^{[14
]}

Sanddal, Nels D. ^{[15
]}

机构：

[1] Carolinas Med Ctr, Div Trauma Surg Crit Care & Acute Care Surg, Dept Surg, Charlotte, NC 28203 USA

[2] Univ Washington, Harborview Med Ctr, Dept Surg, Div Trauma, Seattle, WA 98104 USA

[3] Univ Virginia, Dept Emergency Med, Charlottesville, VA USA

[4] East Carolina Univ, Dept Emergency Med, Greenville, NC USA

[5] Univ Pittsburgh, Dept Surg, Med Ctr Hlth Syst, Pittsburgh, PA USA

[6] Univ Louisville Hosp, Div Pediat Surg, Dept Surg, Louisville, KY USA

[7] Univ Calif Davis, Med Ctr, Div Trauma Acute Care Surg & Surg Crit Care, Dept Surg, Sacramento, CA 95817 USA

[8] Univ Calif San Diego Hlth Syst, Dept Surg, San Diego, CA USA

[9] Anchorage Fire Dept, Anchorage, AK USA

[10] Louisiana State Univ, Dept Surg, New Orleans, LA USA

[11] Mayo Clin, Dept Surg, Div Trauma Crit Care & Gen Surg, Rochester, MN USA

[12] Univ Oklahoma, Sch Community Med, Dept Emergency Med, Tulsa, OK USA

[13] St Mary Trauma Serv, Grand Rapids, MI USA

[14] Rutgers New Jersey Med Sch, Dept Surg, Newark, NJ USA

[15] Amer Coll Surg, Chicago, IL USA

来源：

PREHOSPITAL EMERGENCY CARE | 2016年 / 20卷 / 05期

关键词：

tranexamic acid; trauma; hemorrhage control; emergency medical services; TRAUMA;

D O I：

10.3109/10903127.2016.1142628

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Tranexamic acid (TXA) is being administered already in many prehospital air and ground systems. Insufficient evidence exists to support or refute the prehospital administration of TXA, and results are pending from several prehospital studies currently in progress. We have created this document to aid agencies and systems in best practices for TXA administration based on currently available best evidence. This document has been endorsed by the American College of Surgeons-Committee on Trauma, the American College of Emergency Physicians, and the National Association of EMS Physicians.

引用

页码：557 / 559

页数：3

共 8 条

[1] Intraoperative Tranexamic Acid Reduces Blood Transfusion in Children Undergoing Craniosynostosis Surgery A Randomized Double-blind Study
Dadure, Christophe
Sauter, Magali
Bringuier, Sophie
Bigorre, Michelle
Raux, Olivier
Rochette, Alain
Canaud, Nancy
Capdevila, Xavier
[J]. ANESTHESIOLOGY, 2011, 114 (04) : 856 - 861
[2] The Efficacy of Antifibrinolytic Drugs in Children Undergoing Noncardiac Surgery: A Systematic Review of the Literature
Faraoni, David
Goobie, Susan M.
[J]. ANESTHESIA AND ANALGESIA, 2014, 118 (03) : 628 - 636
[3] Efficacy of Tranexamic Acid in Pediatric Craniosynostosis Surgery A Double-blind, Placebo-controlled Trial
Goobie, Susan M.
Meier, Petra M.
Pereira, Luis M.
McGowan, Francis X.
Prescilla, Randy P.
Scharp, Laurie A.
Rogers, Gary F.
Proctor, Mark R.
Meara, John G.
Soriano, Sulpicio G.
Zurakowski, David
Sethna, Navil F.
[J]. ANESTHESIOLOGY, 2011, 114 (04) : 862 - 871
[4] Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study
Morrison, Jonathan J.
Dubose, Joseph J.
Rasmussen, Todd E.
Midwinter, Mark J.
[J]. ARCHIVES OF SURGERY, 2012, 147 (02) : 113 - 119
[5] Tranexamic acid in trauma: How should we use it?
Napolitano, Lena M.
Cohen, Mitchell J.
Cotton, Bryan A.
Schreiber, Martin A.
Moore, Ernest E.
[J]. JOURNAL OF TRAUMA AND ACUTE CARE SURGERY, 2013, 74 (06) : 1575 - 1586
[6] The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial
Roberts, Ian
Shakur, Haleema
Afolabi, Adefemi
Brohi, Karim
Coats, Tim
Dewan, Yashbir
Gando, Satoshi
Guyatt, Gordon
Hunt, B. J.
Morales, Carlos
Perel, Pablo
Prieto-Merino, David
Woolley, Tom
[J]. LANCET, 2011, 377 (9771) : 1096 - 1101
[7] Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
Shakur, Haleema
Roberts, Ian
Bautista, Raul
Caballero, Jose
Coats, Tim
Dewan, Yashbir
El-Sayed, Hesham
Gogichaishvili, Tamar
Gupta, Sanjay
Herrera, Jorge
Hunt, Beverley
Iribhogbe, Pius
Izurieta, Mario
Khamis, Hussein
Komolafe, Edward
Marrero, Maria-Acelia
Mejia-Mantilla, Jorge
Miranda, Jaime
Morales, Carlos
Olaomi, Oluwole
Dashi, Fatos
Perel, Pablo
Peto, Richard
Ramana, P. V.
Ravi, R. R.
Yutthalcasemsunt, Surakrant
Dakubo, Jonathan
Gogichaishvili, Tamar
Golden, Nyoman
Izurieta, Mario
Khamis, Hussein
Komolafe, Edward
Loria-Castellanos, Jorge
Mejia-Mantilla, Jorge
Miranda, Jaime
Munoz, Angeles
Mutiso, Vincent
Olcwen, Patrick
Ortiz, Zulma
Pascual, Maria
Ravi, R.
Roslani, April
Trenkler, Stefan
Volpi, Annalisa
Yutthakasemsunt, Surakrant
Roberts, Ian
Shakur, Haleema
Perel, Pablo
Bametson, Lin
Ramos, Maria
[J]. LANCET, 2010, 376 (9734) : 23 - 32
[8] Stockinger Z, 2015, E ASS SURG TRAUM ANN

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