Incidental Uptake of 68Ga-DOTATATE Gastrointestinal Stromal Tumor of Duodenum

被引：3

作者：

Koroglu, Gizem ^{[1
]}

Gorur, Gozde Daglioez ^{[1
]}

Dogan, Sevtap ^{[2
]}

Bayrak, Buesra Yaprak ^{[3
]}

Demir, Hakan ^{[1
]}

机构：

[1] Kocaeli Univ, Med Fac, Dept Nucl Med, Kocaeli, Turkey

[2] Kocaeli Univ, Med Fac, Dept Radiol, Kocaeli, Turkey

[3] Kocaeli Univ, Med Fac, Dept Pathol, Kocaeli, Turkey

来源：

CLINICAL NUCLEAR MEDICINE | 2022年 / 47卷 / 03期

关键词：

Ga-68-DOTATATE; incidental; GIST; duodenum; SOMATOSTATIN RECEPTORS;

D O I：

10.1097/RLU.0000000000004036

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

ABSTRACT: A 56-year-old man underwent 68Ga-DOTATATE PET/CT with suspicion of a pancreatic neuroendocrine tumor. However, in this imaging, a mass with 68Ga-DOTATATE uptake was observed not in pancreas but in the duodenojejunal junction. Abdominal tomography confirmed that the heterogeneously enhanced mass was originated from duodenum. The patient was operated, and the histopathology result was evaluated as low-risk gastrointestinal stromal tumor. Although there was low or no specific binding to gastrointestinal stromal tumor cells for all 68Ga-labeled DOTA peptides, uptake of 68Ga-DOTATATE was observed incidentally in this case. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

引用

页码：E289 / E290

页数：2

共 8 条

[1] The role of [68 Ga]Ga-DOTATATE PET/CT in wild-type KIT/PDGFRA gastrointestinal stromal tumours (GIST) [J].

Aloj, Luigi ;

Giger, Olivier ;

Mendichovszky, Iosif A. ;

Challis, Ben G. ;

Ronel, Meytar ;

Harper, Ines ;

Cheow, Heok ;

ten Hoopen, Rogier ;

Pitfield, Deborah ;

Gallagher, Ferdia A. ;

Attili, Bala ;

McLean, Mary ;

Jones, Robin L. ;

Dileo, Palma ;

Bulusu, Venkata Ramesh ;

Maher, Eamonn R. ;

Casey, Ruth T. .

EJNMMI RESEARCH, 2021, 11 (01)

[2] Gastrointestinal stromal tumors (GISTs) express somatostatin receptors and bind radiolabeled somatostatin analogs [J].

Arne, Gabriella ;

Nilsson, Bengt ;

Dalmo, Johanna ;

Kristiansson, Erik ;

Arvidsson, Yvonne ;

Forssell-Aronsson, Eva ;

Nilsson, Ola ;

Ahlman, Hakan .

ACTA ONCOLOGICA, 2013, 52 (04) :783-792

[3]

Braat Arthur J A T, 2017, Lancet Oncol, V18, pe185, DOI 10.1016/S1470-2045(17)30078-5

[4] 68Ga-Labeled bombesin studies in patients with gastrointestinal stromal tumors:: Comparison with 18F-FDG [J].

Dimitrakopoulou-Strauss, Antonia ;

Hohenberger, Peter ;

Haberkorn, Uwe ;

Maecke, Helmut R. ;

Eisenhut, Michael ;

Strauss, Ludwig G. .

JOURNAL OF NUCLEAR MEDICINE, 2007, 48 (08) :1245-1250

[5]

Loaiza-Bonilla A, 2017, CUREUS J MED SCIENCE, V9, DOI 10.7759/cureus.1710

[6] Targeting Gastrointestinal Stromal Tumor with 68Ga-Labeled Peptides: An In Vitro Study on Gastrointestinal Stromal Tumor-Cell Lines [J].

Paulmichl, Achim ;

Summer, Dominik ;

Manzl, Claudia ;

Rangger, Christine ;

Orlandi, Francesca ;

Niedermoser, Sabrina ;

Taguchi, Takahiro ;

Waengler, Bjoern ;

Decristoforo, Clemens .

CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 2016, 31 (08) :302-310

[7] High expression of peptide receptors as a novel target in gastrointestinal stromal tumours [J].

Reubi, JC ;

Körner, M ;

Waser, B ;

Mazzucchelli, L ;

Guillou, L .

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2004, 31 (06) :803-810

[8]

Zhao WY, 2014, AM J TRANSL RES, V6, P831

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