Thyroid storm caused by a partial hydatidiform mole

被引：22

作者：

Chiniwala, Niyati U. ^{[1
]}

Woolf, Paul D. ^{[1
]}

Bruno, Christopher P. ^{[1
]}

Kaur, Sukhjinder ^{[1
]}

Spector, Harvey ^{[2
]}

Yacono, Kelli ^{[1
]}

机构：

[1] Crozer Chester Med Ctr, Dept Med, Upland, PA 19013 USA

[2] Crozer Chester Med Ctr, Dept Pathol, Upland, PA 19013 USA

来源：

THYROID | 2008年 / 18卷 / 04期

关键词：

D O I：

10.1089/thy.2007.0212

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Clinical thyrotoxicosis is rare in molar pregnancy and has yet to be reported in a patient with a partial mole. Human chorionic gonadotropin ( hCG), which has thyrotropic activity, is believed to be responsible for hyperthyroidism of gestational trophoblastic activity and hyperemesis gravidarum. We report the first case of hyperthyroidism presenting as thyroid storm in a partial molar pregnancy. Normal thyroid function returned after the partial mole was evacuated, and the biochemical improvement correlated with declining hCG levels. This case highlights the importance of including partial mole in the differential of hCG-mediated hyperthyroidism.

引用

页码：479 / 481

页数：3

共 20 条

[1]

BERKOWITZ RS, 1985, OBSTET GYNECOL, V66, P677

[2]

BERKOWITZ RS, 1987, J REPROD MED, V32, P634

[3] LIFE-THREATENING THYROTOXICOSIS - THYROID STORM [J].

BURCH, HB ;

WARTOFSKY, L .

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 1993, 22 (02) :263-277

[4] Severe hyperthyroidism requiring therapeutic plasmapheresis in a patient with hydatidiform mole [J].

Erbil, Yesim ;

Tihan, Deniz ;

Azezli, Adil ;

Salmaslioglu, Artur ;

Oezluek, Yasemin ;

Bueyuekoeren, Ahmet ;

Oezarmagan, Selcuk .

GYNECOLOGICAL ENDOCRINOLOGY, 2006, 22 (07) :402-404

[5] Gestatioinal trophoblastic disease [J].

Garner, Elizabeth I. O. ;

Goldstein, Donald P. ;

Feltmate, Colleen M. ;

Berkowitz, Ross S. .

CLINICAL OBSTETRICS AND GYNECOLOGY, 2007, 50 (01) :112-122

[6] The regulation of thyroid function in pregnancy: Pathways of endocrine adaptation from physiology to pathology [J].

Glinoer, D .

ENDOCRINE REVIEWS, 1997, 18 (03) :404-433

[7] GOITER AND PREGNANCY - A NEW INSIGHT INTO AN OLD PROBLEM [J].

GLINOER, D ;

LEMONE, M .

THYROID, 1992, 2 (01) :65-70

[8] DIFFERENCES BETWEEN THYROID STIMULATOR IN HYDATIDIFORM MOLE AND HUMAN CHORIONIC THYROTROPIN [J].

HERSHMAN, JM ;

HIGGINS, HP ;

STARNES, WR .

METABOLISM, 1970, 19 (10) :735-&

[9] HYDATIDIFORM MOLE - A COUSE OF CLINICAL HYPERTHYROIDISM - REPORT OF 2 CASES WITH EVIDENCE THAT MOLAR TISSUE SECRETED A THYROID STIMULATOR [J].

HERSHMAN, JM ;

HIGGINS, HP .

NEW ENGLAND JOURNAL OF MEDICINE, 1971, 284 (11) :573-+

[10] THYROTOXICOSIS OF HYDATIDIFORM MOLE [J].

HIGGINS, HP ;

HERSHMAN, JM ;

KENIMER, JG ;

PATILLO, RA ;

BAYLEY, TA ;

WALFISH, P .

ANNALS OF INTERNAL MEDICINE, 1975, 83 (03) :307-311

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