Clopidogrel Treatment during Pregnancy: A Case Report and a Review of Literature

被引:34
作者
De Santis, Marco [1 ]
De Luca, Carmen [1 ]
Mappa, Ilenia [1 ]
Cesari, Elena [1 ]
Mazza, Andrea [1 ]
Quattrocchi, Tomasella [1 ]
Caruso, Alessandro [1 ]
机构
[1] Univ Cattolica Sacro Cuore, Dept Obstet & Gynaecol, Telefono Rosso Teratol Informat Serv, I-20123 Milan, Italy
关键词
clopidogrel; pregnancy; coronary artery disease; myocardial infarction; antiplatelet treatment; teratology; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; ACUTE MYOCARDIAL-INFARCTION; CORONARY-ARTERY; ASPIRIN; HYPERTENSION; RATS; THERAPY; RISK;
D O I
10.2169/internalmedicine.50.5294
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Management of ischemic heart disease in pregnant women is still difficult, as there is little experience with many of the newer treatments such as clopidogrel. The safety of clopidogrel in pregnancy is unknown, especially in combination with aspirin. Its use during gestation has been described in a few case reports. We describe the case of a 36-year-old woman in her 9th week of pregnancy with a history of chronic hypertension, dyslipidemia and CAD, who required antiplatelet treatment. Clopidogrel and aspirin were administrated until one week before delivery and a healthy child was born at 36 weeks of pregnancy by caesarean section, without any complication.
引用
收藏
页码:1769 / 1773
页数:5
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