Evolutionary origins of STIM1 and STIM2 within ancient Ca2+ signaling systems

被引：81

作者：

Collins, Sean R. ^{[1
]}

Meyer, Tobias ^{[1
]}

机构：

[1] Stanford Univ, Dept Chem & Syst Biol, Stanford, CA 94305 USA

来源：

TRENDS IN CELL BIOLOGY | 2011年 / 21卷 / 04期

关键词：

CRAC CHANNEL ACTIVATION; OPERATED CALCIUM-ENTRY; WIDE RNAI SCREEN; EF-HAND PROTEIN; ENDOPLASMIC-RETICULUM; PLASMA-MEMBRANE; DICTYOSTELIUM-DISCOIDEUM; SACCHAROMYCES-CEREVISIAE; GOLGI-APPARATUS; CA2+-DEPENDENT INACTIVATION;

D O I：

10.1016/j.tcb.2011.01.002

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Human stromal interaction molecule (STIM) proteins are parts of elaborate eukaryotic Ca2+ signaling systems that include numerous plasma membrane (PM), endoplasmic reticulum (ER), and mitochondrial Ca2+ transporters, channels and regulators. STIM2 and STIM1 function as Ca2+ sensors with different sensitivities for ER Ca2+. They translocate to ER-PM junctions and open PM Orai Ca2+ influx channels when receptor-mediated Ca2+ release lowers ER Ca2+ levels. The resulting increase in cytosolic Ca2+ leads to the activation of numerous Ca2+ effector proteins that in turn regulate differentiation, cell contraction, secretion and other cell functions. In this review, we use an evolutionary perspective to survey molecular activation mechanisms in the Ca2+ signaling system, with a particular focus on regulatory motifs and functions of the two STIM proteins. We discuss the presence and absence of STIM genes in different species, the order of appearance of STIM versus Orai, and the evolutionary addition of new signaling domains to STIM proteins.

引用

页码：202 / 211

页数：10

共 104 条

[1] The genome sequence of Drosophila melanogaster [J].

Adams, MD ;

Celniker, SE ;

Holt, RA ;

Evans, CA ;

Gocayne, JD ;

Amanatides, PG ;

Scherer, SE ;

Li, PW ;

Hoskins, RA ;

Galle, RF ;

George, RA ;

Lewis, SE ;

Richards, S ;

Ashburner, M ;

Henderson, SN ;

Sutton, GG ;

Wortman, JR ;

Yandell, MD ;

Zhang, Q ;

Chen, LX ;

Brandon, RC ;

Rogers, YHC ;

Blazej, RG ;

Champe, M ;

Pfeiffer, BD ;

Wan, KH ;

Doyle, C ;

Baxter, EG ;

Helt, G ;

Nelson, CR ;

Miklos, GLG ;

Abril, JF ;

Agbayani, A ;

An, HJ ;

Andrews-Pfannkoch, C ;

Baldwin, D ;

Ballew, RM ;

Basu, A ;

Baxendale, J ;

Bayraktaroglu, L ;

Beasley, EM ;

Beeson, KY ;

Benos, PV ;

Berman, BP ;

Bhandari, D ;

Bolshakov, S ;

Borkova, D ;

Botchan, MR ;

Bouck, J ;

Brokstein, P .

SCIENCE, 2000, 287 (5461) :2185-2195

[2] THE YEAST CA-2+-ATPASE HOMOLOG, PMR1, IS REQUIRED FOR NORMAL GOLGI FUNCTION AND LOCALIZES IN A NOVEL GOLGI-LIKE DISTRIBUTION [J].

ANTEBI, A ;

FINK, GR .

MOLECULAR BIOLOGY OF THE CELL, 1992, 3 (06) :633-654

[3] The genome of the diatom Thalassiosira pseudonana:: Ecology, evolution, and metabolism [J].

Armbrust, EV ;

Berges, JA ;

Bowler, C ;

Green, BR ;

Martinez, D ;

Putnam, NH ;

Zhou, SG ;

Allen, AE ;

Apt, KE ;

Bechner, M ;

Brzezinski, MA ;

Chaal, BK ;

Chiovitti, A ;

Davis, AK ;

Demarest, MS ;

Detter, JC ;

Glavina, T ;

Goodstein, D ;

Hadi, MZ ;

Hellsten, U ;

Hildebrand, M ;

Jenkins, BD ;

Jurka, J ;

Kapitonov, VV ;

Kröger, N ;

Lau, WWY ;

Lane, TW ;

Larimer, FW ;

Lippmeier, JC ;

Lucas, S ;

Medina, M ;

Montsant, A ;

Obornik, M ;

Parker, MS ;

Palenik, B ;

Pazour, GJ ;

Richardson, PM ;

Rynearson, TA ;

Saito, MA ;

Schwartz, DC ;

Thamatrakoln, K ;

Valentin, K ;

Vardi, A ;

Wilkerson, FP ;

Rokhsar, DS .

SCIENCE, 2004, 306 (5693) :79-86

[4] Global trends of whole-genome duplications revealed by the ciliate Paramecium tetraurelia [J].

Aury, Jean-Marc ;

Jaillon, Olivier ;

Duret, Laurent ;

Noel, Benjamin ;

Jubin, Claire ;

Porcel, Betina M. ;

Segurens, Beatrice ;

Daubin, Vincent ;

Anthouard, Veronique ;

Aiach, Nathalie ;

Arnaiz, Olivier ;

Billaut, Alain ;

Beisson, Janine ;

Blanc, Isabelle ;

Bouhouche, Khaled ;

Camara, Francisco ;

Duharcourt, Sandra ;

Guigo, Roderic ;

Gogendeau, Delphine ;

Katinka, Michael ;

Keller, Anne-Marie ;

Kissmehl, Roland ;

Klotz, Catherine ;

Koll, France ;

Le Mouel, Anne ;

Lepere, Gersende ;

Malinsky, Sophie ;

Nowacki, Mariusz ;

Nowak, Jacek K. ;

Plattner, Helmut ;

Poulain, Julie ;

Ruiz, Francoise ;

Serrano, Vincent ;

Zagulski, Marek ;

Dessen, Philippe ;

Betermier, Mireille ;

Weissenbach, Jean ;

Scarpelli, Claude ;

Schaechter, Vincent ;

Sperling, Linda ;

Meyer, Eric ;

Cohen, Jean ;

Wincker, Patrick .

NATURE, 2006, 444 (7116) :171-178

[5] Coupling of STIM1 to store-operated Ca2+ entry through its constitutive and inducible movement in the endoplasmic reticulum [J].

Baba, Yoshihiro ;

Hayashit, Kenji ;

Fujii, Yoko ;

Mizushima, Akiko ;

Watarai, Hiroshi ;

Wakamori, Minoru ;

Numaga, Takuro ;

Mori, Yasuo ;

Iino, Masamitsu ;

Hikida, Masaki ;

Kurosaki, Tomohiro .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (45) :16704-16709

[6] INOSITOL 1,4,5-TRISPHOSPHATE RELEASES CA2+ FROM VACUOLAR MEMBRANE-VESICLES OF SACCHAROMYCES-CEREVISIAE [J].

BELDE, PJM ;

VOSSEN, JH ;

BORSTPAUWELS, GWFH ;

THEUVENET, APR .

FEBS LETTERS, 1993, 323 (1-2) :113-118

[7]

Berg J.M., 2007, Biochemistry, V6th

[8] STIM2 Regulates Capacitive Ca2+ Entry in Neurons and Plays a Key Role in Hypoxic Neuronal Cell Death [J].

Berna-Erro, Alejandro ;

Braun, Attila ;

Kraft, Robert ;

Kleinschnitz, Christoph ;

Schuhmann, Michael K. ;

Stegner, David ;

Wultsch, Thomas ;

Eilers, Jens ;

Meuth, Sven G. ;

Stoll, Guido ;

Nieswandt, Bernhard .

SCIENCE SIGNALING, 2009, 2 (93) :ra67

[9] Inositol trisphosphate and calcium signalling mechanisms [J].

Berridge, Michael J. .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2009, 1793 (06) :933-940

[10] BELL-SHAPED CALCIUM-RESPONSE CURVES OF INS(1,4,5)P3-GATED AND CALCIUM-GATED CHANNELS FROM ENDOPLASMIC-RETICULUM OF CEREBELLUM [J].

BEZPROZVANNY, I ;

WATRAS, J ;

EHRLICH, BE .

NATURE, 1991, 351 (6329) :751-754

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