Generating diversity at GABAergic synapses

被引：195

作者：

Cherubini, E ^{[1
]}

Conti, F

机构：

[1] Scuola Int Super Studi Avanzati, Ist Nazl Fis, Mat Unit, Biophys Sector, I-34014 Trieste, Italy

[2] Univ Ancona, Ist Fisiol Umana, I-60020 Ancona, Italy

来源：

TRENDS IN NEUROSCIENCES | 2001年 / 24卷 / 03期

关键词：

D O I：

10.1016/S0166-2236(00)01724-0

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

GABA-mediated transmission is characterized by high variability of synaptic responses. Major contributors to this variability are: presynaptic factors. including release probability and number of release sites; factors that determine synaptic GABA transients in the cleft, including diffusion and the actions of GABA transporters; and postsynaptic factors, including GABA, receptors subtypes, their location and number, their modulation by endogenous and exogenous factors, and their interactions with postsynaptic-anchoring proteins.

引用

页码：155 / 162

页数：8

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