Alkaloids and amides from Glycosmis macrophylla

被引:22
作者
Cheenpracha, Sarot [2 ]
Laphookhieo, Surat [1 ]
机构
[1] Mae Fah Luang Univ, Nat Prod Res Lab, Sch Sci, Muang 57100, Chiangrai, Thailand
[2] Univ Phayao, Sch Sci, Muang 56000, Phayao, Thailand
关键词
Glycosmis macrophylla; Rutaceae; Carbazole alkaloids; Amides; CARBAZOLE ALKALOIDS; CHEMICAL-CONSTITUENTS; ARBOREA; ROOTS;
D O I
10.1016/j.phytol.2011.03.002
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Phytochemical investigation of the roots and twigs of Glycosmis macrophylla yielded a new carbazole alkaloid, glycrophylamine (1), and a new amide, glycrophylamide (6) together with five known compounds. The structures of these compounds were determined by spectral analyses. Some of the isolated compounds were evaluated for cytotoxicity against NCI-H187 cancer cell line. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:187 / 189
页数:3
相关论文
共 10 条
[1]  
BHATTACHARYYA P, 1985, MED CHEM, V24, P2
[2]   Carbazole alkaloids from roots of Glycosmis arborea [J].
Chakravarty, AK ;
Sarkar, T ;
Masuda, K ;
Shiojima, K .
PHYTOCHEMISTRY, 1999, 50 (07) :1263-1266
[3]   A new dimeric carbazole alkaloid from Glycosmis stenocarpa roots [J].
Cuong, NM ;
Hung, TQ ;
Van Sung, T ;
Taylor, WC .
CHEMICAL & PHARMACEUTICAL BULLETIN, 2004, 52 (10) :1175-1178
[4]   Bioactive amides from Glycosmis species [J].
Greger, H ;
Zechner, G ;
Hofer, O ;
Vajrodaya, S .
JOURNAL OF NATURAL PRODUCTS, 1996, 59 (12) :1163-1168
[5]  
Hofer O, 2000, PROG CH ORG NAT PROD, V80, P187
[6]   Chemical constituents of Glycosmis arborea:: Three new carbazole alkaloids and their biological activity [J].
Ito, C ;
Itoigawa, M ;
Sato, A ;
Hasan, CM ;
Rashid, MA ;
Tokuda, H ;
Mukainaka, T ;
Nishino, H ;
Furukawa, H .
JOURNAL OF NATURAL PRODUCTS, 2004, 67 (09) :1488-1491
[7]  
Ito C, 2000, CHEM PHARM BULL, V48, P65
[8]   NEW COLORIMETRIC CYTOTOXICITY ASSAY FOR ANTICANCER-DRUG SCREENING [J].
SKEHAN, P ;
STORENG, R ;
SCUDIERO, D ;
MONKS, A ;
MCMAHON, J ;
VISTICA, D ;
WARREN, JT ;
BOKESCH, H ;
KENNEY, S ;
BOYD, MR .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1990, 82 (13) :1107-1112
[9]  
SUKARI MA, 2007, J ULTRA SCI PHYS SCI, V19, P139
[10]   Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities [J].
Wang, JS ;
Zheng, YT ;
Efferth, T ;
Wang, RR ;
Shen, YM ;
Hao, XJ .
PHYTOCHEMISTRY, 2005, 66 (06) :697-701