Solvent free synthesis of amidoalkyl derivatives under green and convenient conditions

被引：9
作者：
Sadeghi, Seyyed Hojjat [1 ]
Moradi, Leila [1 ]
机构：
[1] Univ Kashan, Fac Chem, Dept Organ Chem, POB 8731753153, Kashan, Iran
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2022年 / 59卷 / 04期
关键词：
ONE-POT SYNTHESIS; EFFICIENT SYNTHESIS; MULTICOMPONENT SYNTHESIS; SULFONIC-ACID; CATALYTIC APPLICATION; REUSABLE CATALYST; RAPID SYNTHESIS; BETA-NAPHTHOL; IONIC LIQUID; 1-AMIDOALKYL-2-NAPHTHOLS;
D O I：
10.1002/jhet.4409
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Amidoalkyl derivatives are significant compounds due to their application in the preparation of potent drugs and important biological compounds. In this context, we presented a new method for the synthesis of amido alkyl beta-naphthol and amidoalky naphthoquinones using ascorbic acid (vitamin C) as a natural and water-soluble catalyst under solvent-free conditions. Short reaction time, high yield of product, easy workup and low cost of catalyst are some of the advantages of this method. All the products were obtained in high to excellent yields and characterized by (HNMR)-H-1, (CNMR)-C-13, and FT-IR methods.
引用
收藏
页码：695 / 703
页数：9
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