Ambient temperature and the pituitary hormone responses to exercise in humans

被引:25
作者
Bridge, MW [1 ]
Weller, AS
Rayson, M
Jones, DA
机构
[1] Univ Birmingham, Sch Sport & Exercise Sci, Birmingham B15 2TT, W Midlands, England
[2] QinetiQ Ltd, Ctr Human Sci, Farnborough GU14 0LX, Hants, England
[3] Optimal Performance Ltd, Farnham GU9 7EB, Surrey, England
关键词
D O I
10.1113/eph8802593
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Pituitary hormones have an important role during exercise yet relatively little is known about the stimulus for their release. Body temperature progressively increases during prolonged steady-state exercise in the heat and we have investigated the role that this may play in the release of prolactin, growth hormone and cortisol (as an indicator of adrenocorticotropic hormone) into the circulation. Fit young male subjects exercised at 73 % <(V)over dot>(O2,max) until volitional fatigue at 20degreesC and at 35degreesC (30 % relative humidity at both temperatures). Rectal temperature and mean skin temperature were monitored and blood samples analysed for lactate, glucose, cortisol, growth hormone and prolactin concentrations. During the first 20 min, core temperature rose continuously and to a similar extent at both temperatures, while mean skin temperature was approximately 4degreesC lower during exercise in the cool. Blood glucose concentration was essentially constant throughout the period of exercise while lactate concentration increased in the first 10 min and then remained constant with very similar changes in the two exercise conditions. Prolactin and growth hormone concentrations both increased during the exercise period while the concentration of cortisol declined slightly before rising slightly over the 40 min period. Prolactin release was significantly greater when exercise was carried out in the heat while there was no difference in the release of growth hormone or cortisol in the two conditions. When plotted as a function of rectal temperature, growth hormone concentration showed a linear relationship which was the same at ambient temperatures of 35 degreesC and 20 degreesC. Prolactin concentration had a curvilinear relationship with rectal temperature and this differed markedly at the two ambient temperatures. Cortisol concentration showed no dependence on any measure of body temperature. Our results are consistent with some aspect of body temperature being a stimulus for growth hormone and prolactin secretion; however, the precise mechanism clearly differs between the two hormones and we suggest that skin temperature modulates prolactin release, but does not affect the release of growth hormone.
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收藏
页码:627 / 635
页数:9
相关论文
共 32 条
[1]   EFFECT OF PINDOLOL ON ENDOCRINE AND TEMPERATURE RESPONSES TO BUSPIRONE IN HEALTHY-VOLUNTEERS [J].
ANDERSON, IM ;
COWEN, PJ .
PSYCHOPHARMACOLOGY, 1992, 106 (03) :428-432
[2]   The effects of carbohydrate supplementation on immune responses to a soccer-specific exercise protocol [J].
Bishop, NC ;
Blannin, AK ;
Robson, PJ ;
Walsh, NP ;
Gleeson, M .
JOURNAL OF SPORTS SCIENCES, 1999, 17 (10) :787-796
[3]   Carbohydrate beverage ingestion and neutrophil degranulation responses following cycling to fatigue at 75% VO2 max [J].
Bishop, NC ;
Blannin, AK ;
Walsh, NP ;
Gleeson, M .
INTERNATIONAL JOURNAL OF SPORTS MEDICINE, 2001, 22 (03) :226-231
[4]  
BOULANT JA, 1981, FED PROC, V40, P2843
[5]   The impact of heat exposure and repeated exercise on circulating stress hormones [J].
Brenner, IKM ;
Zamecnik, J ;
Shek, PN ;
Shephard, RJ .
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, 1997, 76 (05) :445-454
[6]  
BRIDGE MW, 1999, J PHYSIOL-LONDON, V521, pP103
[7]   EVIDENCE FOR AN INTERFERENCE OF SELECTIVE FACE VENTILATION ON HYPERPROLACTINEMIA INDUCED BY HYPERTHERMIC TREADMILL RUNNING [J].
BRISSON, GR ;
BOUCHARD, J ;
PERONNET, F ;
BOISVERT, P ;
GARCEAU, F .
INTERNATIONAL JOURNAL OF SPORTS MEDICINE, 1987, 8 (06) :387-391
[8]   PROLACTINOTROPHIC EFFECT OF ENDOGENOUS AND EXOGENOUS HEAT LOADS IN HUMAN MALE-ADULTS [J].
BRISSON, GR ;
PERONNET, F ;
PERRAULT, H ;
BOISVERT, P ;
MASSICOTTE, D ;
GAREAU, R .
JOURNAL OF APPLIED PHYSIOLOGY, 1991, 70 (03) :1351-1355
[9]   EXERCISE-INDUCED BLOOD PROLACTIN VARIATIONS IN TRAINED ADULT MALES - A THERMAL-STRESS MORE THAN AN OSMOTIC-STRESS [J].
BRISSON, GR ;
AUDET, A ;
LEDOUX, M ;
MATTON, P ;
PELLERINMASSICOTTE, J ;
PERONNET, F .
HORMONE RESEARCH, 1986, 23 (04) :200-206
[10]   EXERCISE AS A SCREENING-TEST FOR GROWTH-HORMONE RELEASE [J].
BUCKLER, JMH .
ACTA ENDOCRINOLOGICA, 1972, 69 (02) :219-&