T cell expansion: The Survivin interface between cell proliferation and cell death

被引：7

作者：

Altieri, DC ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Ctr Canc, Dept Canc Biol, Worcester, MA 01605 USA

来源：

IMMUNITY | 2005年 / 22卷 / 05期

关键词：

D O I：

10.1016/j.immuni.2005.05.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

T cell proliferation is tightly controlled by intersecting signaling networks. In this issue of Immunity, Song et al. (2005) uncover Survivin as a new mediator of this process. Abundantly studied as a cancer gene, Survivin now emerges as an essential arbiter of T cell expansion, coupling cell cycle progression to apoptosis resistance.

引用

页码：534 / 535

页数：2

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