T cell expansion: The Survivin interface between cell proliferation and cell death

被引：7
|
作者：
Altieri, DC [1 ]
机构：
[1] Univ Massachusetts, Sch Med, Ctr Canc, Dept Canc Biol, Worcester, MA 01605 USA
来源：
IMMUNITY | 2005年 / 22卷 / 05期
关键词：
D O I：
10.1016/j.immuni.2005.05.001
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
T cell proliferation is tightly controlled by intersecting signaling networks. In this issue of Immunity, Song et al. (2005) uncover Survivin as a new mediator of this process. Abundantly studied as a cancer gene, Survivin now emerges as an essential arbiter of T cell expansion, coupling cell cycle progression to apoptosis resistance.
引用
收藏
页码：534 / 535
页数：2
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