Modelling polycystic kidney disease

被引：1

作者：

Romagnani, Paola ^{[1
,2
,3
]}

机构：

[1] Univ Florence, Meyer Childrens Hosp, Dept Biomed & Expt Sci Mario Serio, I-50139 Florence, Italy

[2] Univ Florence, Meyer Childrens Hosp, Excellence Ctr Res Transfer & High Educ Dev DE NO, I-50139 Florence, Italy

[3] Univ Florence, Meyer Childrens Hosp, Pediat Nephrol Unit, I-50139 Florence, Italy

来源：

NATURE MATERIALS | 2017年 / 16卷 / 11期

关键词：

AUTOSOMAL-DOMINANT;

D O I：

10.1038/nmat5013

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Cysts were generated from organoids in vitro and the removal of adherent cues was shown to play a key role in polycystic kidney disease progression. These cysts resembled those of diseased tissue phenotypically and were capable of remodelling their microenvironment.

引用

页码：1058 / 1059

页数：2

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