Versatile symport transporters based on cyclic peptide dimers

被引：13
作者：
Fuertes, Alberto [1 ]
Amorin, Manuel [1 ]
Granja, Juan R. [1 ]
机构：
[1] Univ Santiago de Compostela USC, Singular Res Ctr Chem Biol & Mol Mat, Dept Organ Chem, CIQUS, Santiago De Compostela 15782, Spain
来源：
CHEMICAL COMMUNICATIONS | 2020年 / 56卷 / 01期
关键词：
POWERFUL; IONS;
D O I：
10.1039/c9cc06644f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We present the synthesis and transmembrane transport properties of a new family of tris-pyridine-decorated cyclic peptides. These molecules are designed to self-assemble into dimeric shuttles in nonpolar media, which act as symport ionophores in which, apparently, the tris-pyridine scaffold complexes both cations and anions with high potency and efficacy.
引用
收藏
页码：46 / 49
页数：4
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