Pharmacological Targets in Chronic Heart Failure with Reduced Ejection Fraction

被引：2
作者：
Moloce, Maria-Angela [1 ]
Costache, Irina-Iuliana [1 ,2 ]
Nicolae, Ana [2 ]
Onofrei Aursulesei, Viviana [1 ,2 ]
机构：
[1] Iasi St Spiridon Cty Hosp, Iasi 700111, Romania
[2] Iasi Grigore T Popa Univ Med & Pharm, Dept Internal Med Cardiol, Iasi 700111, Romania
来源：
LIFE-BASEL | 2022年 / 12卷 / 08期
关键词：
heart failure with reduced ejection fraction; novel pharmacological targets; trials; DOUBLE-BLIND; TRANSLATIONAL RESEARCH; FERRIC CARBOXYMALTOSE; RATIONALE; MORTALITY; THERAPY; HOSPITALIZATION; MULTICENTER; EFFICACY; OUTCOMES;
D O I：
10.3390/life12081112
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Heart failure management has been repeatedly reviewed over time. This strategy has resulted in improved quality of life, especially in patients with heart failure with reduced ejection fraction (HFrEF). It is for this reason that new mechanisms involved in the development and progression of heart failure, along with specific therapies, have been identified. This review focuses on the most recent guidelines of therapeutic interventions, trials that explore novel therapies, and also new molecules that could improve prognosis of different HFrEF phenotypes.
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