Magnetic Resonance-Guided Focused Ultrasound Thalamotomy to Treat Essential Tremor in Nonagenarians

被引：13

作者：

Paff, Michelle ^{[1
]}

Boutet, Alexandre ^{[1
,2
]}

Neudorfer, Clemens ^{[1
]}

Elias, Gavin J. B. ^{[1
]}

Germann, Jurgen ^{[1
]}

Loh, Aaron ^{[1
]}

Kucharczyk, Walter ^{[1
,2
]}

Fasano, Alfonso ^{[3
,4
]}

Schwartz, Michael L. ^{[5
]}

Lozano, Andres M. ^{[1
,6
]}

机构：

[1] Univ Hlth Network, Toronto, ON, Canada

[2] Univ Toronto, Joint Dept Med Imaging, Toronto, ON, Canada

[3] Univ Toronto, Univ Hlth Network, Toronto Western Hosp,Div Neurol, Edmond J Safra Program Parkinsons Dis,Morton & Gl, Toronto, ON, Canada

[4] Krembil Brain Inst, Toronto, ON, Canada

[5] Univ Toronto, Sunnybrook Hlth Sci Ctr, Div Neurosurg, Toronto, ON, Canada

[6] Univ Toronto, Toronto Western Hosp, Dept Surg, Div Neurosurg, West Wing 4-431,399 Bathurst St, Toronto, ON M5T 2S8, Canada

来源：

STEREOTACTIC AND FUNCTIONAL NEUROSURGERY | 2020年 / 98卷 / 03期

关键词：

Focused ultrasound; Essential tremor; Thalamotomy; Advanced age; QUALITY-OF-LIFE; PREVALENCE; DISABILITY;

D O I：

10.1159/000506817

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Essential tremor (ET) is a disabling movement disorder that is most prevalent among the elderly. While deep brain stimulation surgery targeting the ventral intermediate nucleus of the thalamus is commonly used to treat ET, the most elderly patients or those with multiple medical comorbidities may not qualify as surgical candidates. Magnetic resonance-guided focused ultrasound (MRgFUS) constitutes a less invasive modality that may be used to perform thalamotomy without the need for a burr hole craniotomy. Here, we report on 2 patients over the age of 90 years who benefited significantly from MRgFUS thalamotomy to relieve their symptoms and improve their quality of life. The procedure was well tolerated and performed safely in both patients. We conclude that age should not be a limiting factor in the treatment of patients with MRgFUS.

引用

页码：182 / 186

页数：5

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