Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human -: art. no. R60

被引:70
作者
Magness, CL
Fellin, PC
Thomas, MJ
Korth, MJ
Agy, MB
Proll, SC
Fitzgibbon, M
Scherer, CA
Miner, DG
Katze, MG
Iadonato, SP
机构
[1] Illumigen Biosci Inc, Seattle, WA 98134 USA
[2] Univ Washington, Dept Microbiol, Seattle, WA 98195 USA
[3] Univ Washington, Washington Natl Primate Res Ctr, Seattle, WA 98195 USA
关键词
D O I
10.1186/gb-2005-6-7-r60
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
We report the initial sequencing and comparative analysis of the Macaca mulatta transcriptome. Cloned sequences from 11 tissues, nine animals, and three species ( M. mulatta, M. fascicularis, and M. nemestrina) were sampled, resulting in the generation of 48,642 sequence reads. These data represent an initial sampling of the putative rhesus orthologs for 6,216 human genes. Mean nucleotide diversity within M. mulatta and sequence divergence among M. fascicularis, M. nemestrina, and M. mulatta are also reported.
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页数:16
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