Low 2016/17 season vaccine effectiveness against hospitalised influenza A(H3N2) among elderly: awareness warranted for 2017/18 season

被引:21
作者
Rondy, Marc [1 ]
Gherasim, Alin [2 ,3 ]
Casado, Itziar [3 ,4 ]
Launay, Odile [5 ,6 ]
Rizzo, Caterina [7 ]
Pitigoi, Daniela [8 ]
Mickiene, Aukse [9 ]
Marbus, Sierk D. [10 ]
Machado, Ausenda [11 ]
Syrjanen, Ritva K. [12 ]
Pem-Novose, Iva [13 ]
Horvath, Judith Krisztina [14 ]
Larrauri, Amparo [2 ,3 ]
Castilla, Jesus [3 ,4 ]
Vanhems, Philippe [5 ,15 ,16 ]
Alfonsi, Valeria [7 ]
Ivanciuc, Alina E. [17 ]
Kuliese, Monika [9 ]
van Gageldonk-Lafeber, Rianne [10 ]
Gomez, Veronica [11 ]
Ikonen, Niina [18 ]
Lovric, Zvjezdana [13 ]
Ferenczi, Annamaria [14 ]
Moren, Alain [1 ]
机构
[1] EpiConcept, Paris, France
[2] Inst Hlth Carlos III, Natl Ctr Epidemiol, Madrid, Spain
[3] Inst Hlth Carlos III, CIBER Epidemiol & Salud Publ, Madrid, Spain
[4] IdiSNA, Inst Salud Publ Navarra, Pamplona, Spain
[5] INSERM, F CRIN, Innovat Clin Res Network Vaccinol I REIVAC, CIC 1417, Paris, France
[6] Univ Paris 05, Sorbonne Paris Cite, CIC Cochin Pasteur, AP HP, Paris, France
[7] Ist Super Sanita, Rome, Italy
[8] Univ Med & Pharm Carol Davila, Natl Inst Res Cantacuzino, Bucharest, Romania
[9] Lithuanian Univ Hlth Sci, Dept Infect Dis, Kaunas, Lithuania
[10] Natl Inst Publ Hlth & Environm RIVM, Ctr Infect Dis Control, Ctr Epidemiol & Surveillance Infect Dis, Bilthoven, Netherlands
[11] Natl Hlth Inst Doutor Ricardo Jorge, Epidemiol Dept, Epidemiol Res Unit, Lisbon, Portugal
[12] Natl Inst Hlth & Welf, Impact Assessment Unit, Tampere, Finland
[13] Croatian Inst Publ Hlth, Epidemiol Serv, Zagreb, Croatia
[14] Off Chief Med Officer, Budapest, Hungary
[15] Hosp Civils Lyon, Hop Edouard Herriot, Infect Control & Epidemiol Unit, Lyon, France
[16] Univ Claude Bernard Lyon 1, Ecole Natl Super ENS Lyon, UMR5308,Emerging Pathogens Lab, CNRS,INSERM,U1111,Ctr Int Rech Infectiol,Fdn Meri, Lyon, France
[17] Univ Bucharest, Fac Biol, Natl Inst Res Cantacuzino, Bucharest, Romania
[18] Natl Inst Hlth & Welf, Unit Expert Microbiol, Helsinki, Finland
关键词
EUROPE;
D O I
10.2807/1560-7917.ES.2017.22.41.17-00645
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
In a multicentre European hospital study we measured influenza vaccine effectiveness (IVE) against A(H3N2) in 2016/17. Adjusted IVE was 17% (95% confidence interval (CI): 1 to 31) overall; 25% (95% CI: 2 to 43) among 65-79-year-olds and 13% (95% CI: -15 to 30) among those >= 80 years. As the A(H3N2) vaccine component has not changed for 2017/18, physicians and public health experts should be aware that IVE could be low where A(H3N2) viruses predominate.
引用
收藏
页码:8 / 13
页数:6
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