Racial Differences in Depressive Symptoms and Self-Rated Health Among Breast Cancer Survivors on Aromatase Inhibitor Therapy

被引:13
作者
Calhoun, Carla [1 ]
Helzlsouer, Kathy J. [1 ,2 ]
Gallicchio, Lisa [1 ,2 ,3 ]
机构
[1] Mercy Med Ctr, Weinberg Ctr Womens Hlth & Med, Prevent & Res Ctr, Baltimore, MD 21202 USA
[2] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA
[3] Univ Maryland, Dept Epidemiol & Publ Hlth, Baltimore, MD 21201 USA
关键词
estrogen; estrogen receptor positive; endocrine therapy; self-rated health; depression; breast cancer; aromatase inhibitors; QUALITY-OF-LIFE; POSTMENOPAUSAL WOMEN; MENOPAUSAL SYMPTOMS; ADJUVANT TREATMENT; ENDOCRINE THERAPY; TAMOXIFEN; RISK; PAIN; EXEMESTANE; MORTALITY;
D O I
10.1080/07347332.2015.1019661
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
The goal of this survey-based study was to examine whether aromatase inhibitor (AI) therapy was associated with depressive symptoms and self-rated health among Black and White breast cancer survivors (N = 761). Results showed that among Black, but not White, breast cancer survivors current AI therapy was associated with a significant increase in the odds of both depressive symptoms (OR 3.59; 95% CI 1.01, 13.00) and poorer self-rated health (OR 3.16; 95% CI 1.06, 9.46). Presence of pain was significantly associated with increased odds of both outcomes among both groups. The findings underscore the importance of addressing not only physical but mental health among breast cancer survivors on AIs, especially those of Black race.
引用
收藏
页码:263 / 277
页数:15
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