Ocular motor abnormalities in Parkinsonian syndromes

被引：64

作者：

Pinkhardt, Elmar H. ^{[1
]}

Kassubek, Jan ^{[1
]}

机构：

[1] Univ Ulm, Dept Neurol, D-89081 Ulm, Germany

来源：

PARKINSONISM & RELATED DISORDERS | 2011年 / 17卷 / 04期

关键词：

Parkinsonism; Parkinson's disease; Progressive supranuclear palsy; Multiple system atrophy; Oculomotor function; Video-oculography; PROGRESSIVE SUPRANUCLEAR PALSY; FRONTAL EYE FIELD; MULTIPLE SYSTEM ATROPHY; NIGRA PARS RETICULATA; MEMORY-GUIDED SACCADES; SUBTHALAMIC NUCLEUS STIMULATION; DORSOLATERAL PREFRONTAL CORTEX; LATERAL INTRAPARIETAL AREA; DRUG-INDUCED PARKINSONISM; SCLERAL SEARCH COILS;

D O I：

10.1016/j.parkreldis.2010.08.004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Oculomotor abnormalities can be observed in all Parkinsonian syndromes (PS). Nevertheless, due to the considerable overlap of oculomotor pathology in Parkinsonism, oculomotor changes are not generally considered to contribute substantially to the differential diagnosis of PS. Here we review the characteristics of oculomotor disturbances in the major PS, we provide a survey of the current concepts of the underlying neural physiology of oculomotor control and a summary of the major recording techniques for eye movements. The main focus of this review is to outline the subtle differences between apparently similar oculomotor alterations in Parkinson's disease (PD) and atypical neurodegenerative PS that can contribute to the early differential diagnosis of these entities. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：223 / 230

页数：8

共 107 条

[1] Dissociating cognitive deficits involved in voluntary eye movement dysfunctions in Parkinson's disease patients [J].