Antibacterial stilbenoids from the roots of Stemona tuberosa

被引：40

作者：

Lin, Li-Gen ^{[1
]}

Yang, Xin-Zhou ^{[1
]}

Tang, Chun-Ping ^{[1
]}

Ke, Chang-Qiang ^{[1
]}

Zhang, Ji-Bao ^{[1
]}

Ye, Yang ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China

来源：

PHYTOCHEMISTRY | 2008年 / 69卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Stemona tuberosa; Stemonaceae; dihydrostilbenes; stilbostemins N-Y; phenanthraquinone; stemanthraquinone; antibacterial;

D O I：

10.1016/j.phytochem.2007.07.012

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Twelve dihydrostilbenes, stilbostemins N-Y (1-12), and a phenanthraquinone, stemanthraquinone (13), were isolated and identified from roots of Stemona tuberosa, along with five known dihydrostilbenes. Their structures were established on the basis of ID and 2D NMR and other spectroscopic analyses. Dihydrostilbene 8 exhibited strong activity against Bacillus pumilus (MIT 12.5-25 mu g/mL). Many tested compounds exhibited moderate antibacterial activities. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：457 / 463

页数：7

共 11 条

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